지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.11 No.4
- 발행연도
- 2006.12
- 수록면
- 278 - 284 (7page)
이용수
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초록· 키워드
오류제보하기
The beneficial effects of digested onion extracts have been assessed by antimutagenic and anticancer activities by Ames test and SRB test. The total phenolic acids and flavonoids in onion extracts were determined. Red and yellow onions contain more phenolic acids and flavonoids than those in the white onion. Digested, extracts showed antimutagenic activity and anticancer activity, and it appears that the antimutagenic activity of digested extracts of onion against mutagens and anticancer activities were related to their phenols and flavonoids contents. Moreover, the extracts inhibited the proliferation of four human tumorigenic cell lines such as HT-29 (colon), MCF-7 (breast), DU-145 (prostate) and HepG2 (liver), in a dose-dependent manner. Phenolic acids and flavonoids caused oxidative damage to the cancer cell lines and induced apoptosis. Generally, red onion extracts showed effective antimutagenic and anticancer activity, and the digested red onion extracts elicited stronger antimutagenic activity than those of the onion extracts without digestion.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (32)
참고문헌 신청
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Bourne LC, Rice-Evans CA. 1999. Detecting and measuring bioavailability of phenolics and flavonoids in humans: pharmacokinetics of urinary excretion of dietary ferulic acid. In Methods of enzymology. Packer L, ed. Academic Press, Berkeley, California. p 9
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Armstrong B, Doll R. 1975. Environmental factor, cancer incidence and mortality in different countries with special reference to dietary practices. Int J Cancer 15: 617-631.
Kendler BS. 1987. Garlic (Allium sativm) and onion (Allium cepa): a review of their relationship to cardiovascular disease. Print Med 16: 670-685.
Bourne LC, Rice-Evans CA. 1999. Detecting and measuring bioavailability of phenolics and flavonoids in humans: pharmacokinetics of urinary excretion of dietary ferulic acid. In Methods of enzymology. Packer L, ed. Academic Press, Berkeley, California. p 9
Greenwald P. 1992. Colon cancer overview. Cancer 70: 1206-1215.
Armstrong B, Doll R. 1975. Environmental factor, cancer incidence and mortality in different countries with special reference to dietary practices. Int J Cancer 15: 617-631.
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