지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.10 No.1
- 발행연도
- 2005.3
- 수록면
- 46 - 51 (6page)
이용수
초록· 키워드
오류제보하기
The protective effect of Acanthopanax senticosus (AS) extract on alloxan-induced pancreatic β-cell damage was investigated in HIT T-15 cells, a Syrian hamster pancreatic β-cell line. Alloxan caused the pancreatic β-cell damage through the generation of reactive oxygen free radicals, increased DNA fragmentation, and decreased cellular NAD^+ levels. The β-cell damage was significantly prevented by the pretreatment with water soluble extract of AS roots. These results suggest that the protective effect of AS extract, on alloxaninduced β-cell damage, is primarily due to the inhibition of the generation of reactive oxygen free radical species (ROS) by alloxan.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (34)
참고문헌 신청
Dunn JS, Sheehan HL, McLetchie NG. 1943. Necrosis of Langerhans produced experimentally. Lancet I: 484-487.
Rerup CC. 1970. Drugs producing diabetes through damage of insulin secreting cells. Pharmacol Rev 22: 485-518.
Heikkila RE, Barden H, Cohen G. 1974. Prevention of alloxan-induced diabetes by ethanol administration. J Pharmacol Exp Ther 190: 501-506.
Heikkila RE, Winston B, Cohen G, Barden H. 1976. Alloxan-induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate. Biochem Pharmacol 25: 1985-1092.
Cohen G, Heikkila RE. 1974. The generation of hydrogen peroxide, superoxide radical by 6-hydroxyl dopamine, dialuric acid and related agents. J Biol Chem 49: 2447-2452.
Rerup CC. 1970. Drugs producing diabetes through damage of insulin secreting cells. Pharmacol Rev 22: 485-518.
Heikkila RE, Barden H, Cohen G. 1974. Prevention of alloxan-induced diabetes by ethanol administration. J Pharmacol Exp Ther 190: 501-506.
Heikkila RE, Winston B, Cohen G, Barden H. 1976. Alloxan-induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate. Biochem Pharmacol 25: 1985-1092.
Cohen G, Heikkila RE. 1974. The generation of hydrogen peroxide, superoxide radical by 6-hydroxyl dopamine, dialuric acid and related agents. J Biol Chem 49: 2447-2452.
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Cytoprotective Effects of Ethanol Extracts from Korean Fruits and Vegetables on Alloxan-Induced Oxidative Damage in Pancreatic Beta Cell
한국식품영양과학회 학술대회발표집
2012 .10
-
진피 에탄올 추출물이 Alloxan에 의해 유도된 HIT-T15 세포의 산화적 손상에 미치는 영향
한국식품영양과학회지
2010 .08
-
Verification of Antidiabetic Effects of Water Extract and Fraction of Acanthopanax Senticosus senticosus
한국식품영양과학회 학술대회발표집
2016 .10
-
오가피 추출액의 저장조건에 따른 이화학적 특성변화
Food Science and Preservation
2005 .06
-
[P10-53] The Effects of Acanthopanax Senticosus Extracts on Antioxidant Activity and Cell Proliferation/Alkaline Phosphatase Activity in Human Osteoblast-like MG-63 Cell
한국식품영양과학회 학술대회발표집
2006 .10
-
Protective Effect of Acanthopanax senticosus on Oxidative Stress Induced PC12 Cell Death
Food Science and Biotechnology
2007 .12
-
도라지 추출액이 Alloxan 유발 당뇨성 흰쥐의 혈당 및 지질성분에 미치는 영향
한국식품영양과학회지
1996 .12
-
Alloxan 유도 당뇨성 흰쥐에서 조직 중 지질 수준 및 지방산 조성 변화에 관한 연구
한국식품영양과학회지
2004 .10
-
Protective Effects of Peach Extracts against UVB-Induced Skin Damage in HS68 Cells
한국식품영양과학회 학술대회발표집
2014 .10
-
梅實抽出物이 家兎의 Alloxan 糖尿病에 미치는 影響
한국식품영양과학회지
1987 .08
-
가시오가피 추출물이 마크로파지 활성과 우유의 발효 중 젖산균 성장에 미치는 영향
한국축산식품학회지
2007 .01
-
Acanthopanax senticosus Extract Prepared from Cultured Cells Improves Lipid Parameters in Rats Fed with a High Fat Diet
Journal of Food Science and Nutrition
2003 .03
-
[P7-05] Effect of Acanthopanax senticosus Extract on Injury Associated with Hepatic Ischemia and Reperfusion
한국식품영양과학회 학술대회발표집
2006 .10
-
Prevention of Alloxan-induced Diabetes by Se-Methylselenocysteine Pretreatment in Rats : The Effect on Antioxidant System in Pancreas
Journal of Food Science and Nutrition
2009 .06
-
[P8-306] Acanthopanax senticosus extracts exerts anti-inflammatory and anti-oxidant effects
한국식품영양과학회 학술대회발표집
2008 .10
-
[P8-41] Effect of Panax ginseng and Acanthopanax senticosus on Apoptosis induced by Heat Stress
한국식품영양과학회 학술대회발표집
2008 .10
-
[P8-33] Protective Effect of Dieckol on Oxidative Damage in INS-1 Pancreatic β Cells
한국식품영양과학회 학술대회발표집
2010 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-511-018080218