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자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 Journal of Food Science and Nutrition Nutraceuticals and Food Vol.7 No.3
발행연도
2002.9
수록면
332 - 345 (14page)

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It is a recent observation that about 80 per cent of the body's immune system is localized in the gastrointestinal tract. This explains to a large extent why eating right is important for the modulation the immune response and prevention of disease. In addition it is increasingly recognized that the body has an important digestive system also in the lower gastrointestinal tract where numerous important substances are released by microbial enzymes and absorbed. Among these substances are short chain fatty acids, amino acids, various carbohydrates, polyamines, growth factors, coagulation factors, and many thousands of antioxidants, not only traditional vitamins but numerous flavonoids, carotenoids and similar plant- and vegetable produced antioxidants. Also consumption of health-promoting bacteria (probiotics) and vegetable fibres (prebiotics) from numerous sources are known to have strong health-promoting influence. It has been calculated that the intestine harbours about 300,000 genes, which is much more than the calculated about 60,000 for the rest of the human body, indicating a till today totally unexpected metabolic activity in this part of the GI tract. There are seemingly several times more active enzymes in the intestine than in the rest of the body, ready to release hundred thousand or more of substances important for our health and well-being. In addition do the microbial cells produce signal molecules similar to cytokines but called bacteriokines and nitric oxide, with provide modulatory effects both on the mucosal cells, the mucosaassociated lymphoid system (MALT) and the rest of the immune system. Identification of various fermentation products, and often referred to as synbiotics, studies of their role in maintaining health and well-being should be a priority issue during the years to come.

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Abstract

INTRODUCTION

MODERN FOOD CONTAINS LITTLE BACTERIAL COMPONENTS

PROMOTION OF HEALTH THROUGH CONSUMPTION OF PRE - AND PROBIOTICS

WHY A REGULAR BOOSTER DOSE OF PROBIOTICS ?

SUBSTRATE FOR MICROBIAL FERMENTATION (PREBIOTICS) ARE AS IMPORTANT AS BACTERIA (PROBIOTICS)

LARGE AMOUNTS OF HEALTH - PROMOTING BACTERIA NEEDED

GASTROINTESTINAL TRACT OF GREAT IMMUNOLOGICAL IMPORTANCE

LAB - INDUCED STIMULATION OF MACROPHAGE FUNCTION IMPORTANT

CONSUMPTION OF LAB STIMULATES APOPTOSIS

WHY THE POOREST FOOD TO THE SICKEST PATIENTS

CLINICAL EFFECTS OF PROBIOTICS STILL LARGELY UNEXPLORED

PROBIOTICS - AND PREBIOTICS - IN DIARRHEA IN CHILDREN

PROBIOTICS IN ANTIBIOTIC - ASSOCIATED DIARRHEA

PROBIOTICS - AND PREBIOTICS - IN INFLAMMATORY BOWEL DISEASE (IBD)

PROBIOTICS TO CONTROL STOMACH ENVIRONMENT AND HELICOBACTER PYLORI INFECTIONS

USE OF SYNBIOTICS IN THE SICKEST PATIENTS / CRITICAL CARE

CONCLUSION AND FUTURE ASPECTS

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