지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.4
- 발행연도
- 1999.12
- 수록면
- 265 - 269 (5page)
이용수
초록· 키워드
오류제보하기
Taurine is a major β-amino acid in various tissues. Taurine transporter (TAUT) is responsible for the transportation of taurine in the cell. The transporter is affected by various stimuli to maintain its cell volume. Macrophage cell volume varies in its activated states. In our experiment, it was found that the murine macrophage cell line, RAW264.7, expressed TAUT protein in its membrane. Its transportation activities could be blocked by a β-amino acid such as β-alanine, but not by α-amino acids in this cell line. When assessed in RAW264.7 under the influence of immunosuppressive reagents, the activity of the TAUT was decreased by the treatment of rapamycin (RM) or cyclosporin A (CsA). However when ionomycin (IM) was added to this system, TAUT activity was recovered only in CsA-treated cells in a concentration-dependent manner. In order to inhibit the voltage gated Ca^(+2) channel, calmidazolium was added to the RAW264.7 cell line. Treatment of the cell with calmidazolium completely blocked TAUT. Furthermore, addition of IM to this system recovered the activity of TAUT again. When we added phorbol myristate acetate (PMA) to the cell line, secretion of nitric oxide (NO) was increased 4-fold and the TAUT activity was decreased 5-fold. However, the addition of N-nitro L-arginine methyl ester (L-NAME), an inducible NO synthase (iNOS) inhibitor, to the PMA-treated cells, resulted in the recovery of TAUT activity. These results showed that the activity of TAUT was sensitive to the intracellular concentrations of both Ca^(+2) and NO.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
인체 소장상피세포주 모델(HT - 29)에서 β - 알라닌이 타우린수송체 활성에 미치는 영향
한국식품영양과학회지
2001 .04
-
Evaluation of the anti-inflammation activity of natural products in the macrophage cell line RAW 264.7
한국식품영양과학회 학술대회발표집
2013 .11
-
한국인 상용 식물성 식품의 타우린함량 조사
한국식품영양과학회지
1998 .11
-
Taurine Possesses In vitro Antimutagenic Activity Comparable to Major Antioxidants
Journal of Food Science and Nutrition
1999 .03
-
타우린을 첨가한 제과제빵의 베이킹 특성과 섭취가 혈중 알코올 농도에 미치는 영향
한국식품영양학회지
2009 .01
-
시판 음료, 유제품, 당류 및 조미료의 타우린 함량
한국식품영양과학회지
1999 .01
-
우모분에 의한 taurine 강화 계란 생산
한국가금학회 정기총회 및 학술발표회
2004 .11
-
타우린 처리에 의한 나리 기내 식물체 생산체계 최적화
Journal of Plant Biotechnology
2017 .01
-
In vitro Anti-inflammatory Activity of CT extracts in Murine Macrophage RAW264,7 Cells
한국식품영양과학회 학술대회발표집
2011 .10
-
흰쥐의 항염증 및 진통작용에 대한 Glucosamine Hydrochloride와 Taurine 및 그 혼합 투여시의 효과
한국식품영양과학회지
1999 .10
-
[P8-57] The Chemopreventive Potential and Anti-inflammatory Activities of Korean Black Ginseng in Colon26-M3.1 Carcinoma Cells and a Macrophage Cell Line
한국식품영양과학회 학술대회발표집
2009 .11
-
우모 digest에 의한 taurine 강화 계육 생산
한국가금학회 정기총회 및 학술발표회
2003 .11
-
[S4-2] Gene Expression Changes Induced by Taurine in Cultured Human Hepatoma Cells, HepG2
한국식품영양과학회 학술대회발표집
2005 .10
-
[P8-311] 청버섯 에탄올 추출 성분이 Macrophage cell line Raw264.7에서 면역 조절에 미치는 효과
한국식품영양과학회 학술대회발표집
2008 .10
-
Effects of Bifidobacterium Strains Treated with Gastrointestinal Enzymes on Cytokine Induction in RAW 264.7 Macrophage Cells
한국축산식품학회지
2010 .01
-
Immune-enhancing Activity of Polysaccharides Isolated from Ginseng Berry on RAW264.7 Macrophage Cells
한국원예학회 학술발표요지
2019 .05
-
Dietary beet pulp decreases taurine status in dogs fed low protein diet
한국축산학회지
2016 .01
-
사료 내 Carnitine 및 Taurine의 첨가에 의한 산란계의 생산성 및 계란 내 이행에 관한 연구
한국가금학회 정기총회 및 학술발표회
2008 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-511-018075391