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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.1 No.2
- 발행연도
- 1996.12
- 수록면
- 227 - 229 (3page)
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초록· 키워드
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The effects of phenethyl isothiocyanate(PEITC) on xenobiotic metabolizing enzymes and cell kinetics in the target organs for N-nitrosobis(2-oxopropyl)amine(BOP)-tumorigenicity were investigated in female Syrian golden hamsters in order to gain the mechanistic insights into the chemopreventive action of PEITC against BOP-initiated lung and pancreatic carcinogenesis in hamsters. Hamsters were given BOP subcuteneously(s.c.) and/or PEITC by gavage 2h prior to the BOP treatment. Eight and 24h after the PEITC administration, animals were sacrificed for analyzing P450 isoenzymes, glutathine(GSH), glutathione S-transferase(GST) and cell kinetics. The PEITC pretreatment significantly reduced the hepatic P450 isoen ... 전체 초록 보기
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2009-511-018072507