지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학위논문
- 저자정보
- 발행연도
- 2014
- 저작권
- 대전대학교 논문은 저작권에 의해 보호받습니다.
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초록· 키워드
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Objective :
The purpose of this study was to examine the anti-depressive effects of BanHaHuBakTang-kami(BHHBT) on an animal model of depression induced by chronic immobilization stress.
Method :
Immobilization stress was treated to mice for 2 hours for 21 days. To examine effect of BHHBT, we performed Forced Swimming Test (FST), analysis of the neurotransmitter and immunohistochemical staining, measure expression levels of serotonin in the brain.
Results :
BHHBT was decreased immobilization time in forced swimming test.
BHHBT was increased amount of serotonin in the brain.
BHHBT was increased expression levels of serotonin in the brain.
BHHBT was allowed to recover the damaged tissue in the hippocampus region.
BHHBT was reduced the expression level of CRF receptors in paraventricular nucleus.
Conclusions :
These results suggest that BHHBT may have anti-depressive effects on depression.
Key Words :
BanHaHuBakTang-kami(BHHBT), Immobilization stress, Anti-depres-sive effect, Depression, Serotonin
The purpose of this study was to examine the anti-depressive effects of BanHaHuBakTang-kami(BHHBT) on an animal model of depression induced by chronic immobilization stress.
Method :
Immobilization stress was treated to mice for 2 hours for 21 days. To examine effect of BHHBT, we performed Forced Swimming Test (FST), analysis of the neurotransmitter and immunohistochemical staining, measure expression levels of serotonin in the brain.
Results :
BHHBT was decreased immobilization time in forced swimming test.
BHHBT was increased amount of serotonin in the brain.
BHHBT was increased expression levels of serotonin in the brain.
BHHBT was allowed to recover the damaged tissue in the hippocampus region.
BHHBT was reduced the expression level of CRF receptors in paraventricular nucleus.
Conclusions :
These results suggest that BHHBT may have anti-depressive effects on depression.
Key Words :
BanHaHuBakTang-kami(BHHBT), Immobilization stress, Anti-depres-sive effect, Depression, Serotonin
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