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논문 기본 정보

자료유형
학술저널
저자정보
Motoko Kanno (The Cancer Institute Hospital of Japanese Foundation for Cancer Research) Mayu Yunokawa (The Cancer Institute Hospital of Japanese Foundation for Cancer Research) Atsushi Fusegi (Department of Gynecologic Oncology, Cancer Institute Hospital, Tokyo, Japan) Akiko Abe (Cancer Institute Hospital of the Japanese Foundation for Cancer Research) Hidetaka Nomura (Department of Gynecologic Oncology, Cancer Institute Hospital, Tokyo, Japan) Hiroyuki Kanao (Department of Gynecologic Oncology, Cancer Institute Hospital, Tokyo, Japan)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.35 No.4
발행연도
2024.7
수록면
1 - 7 (7page)
DOI
https://doi.org/10.3802/jgo.2024.35.e41

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Objective: The combination of cancer and hypercoagulable states is often called Trousseausyndrome. In particular, cerebral infarction caused by Trousseau syndrome is reported tohave a poor prognosis. In gynecology, there are many reports of ovarian cancer and a fewof uterine cancer. Since there has been no comprehensive report of Trousseau syndrome incer vical cancer, we aimed to summarize Trousseau syndrome in cer vical cancer. Methods: Cerebral infarction caused by cancer-related arterial thrombosis was defined asTrousseau syndrome. Patients with cer vical cancer diagnosed at our hospital between Januar y2014 and December 2021 were retrospectively reviewed using the hospital’s medical records. Results: A total of 1,432 patients were included in the study. Trousseau syndrome occurredin 6 patients (0.4%). The mean age of patients with Trousseau syndrome was 63 years (range:53–78 years). Of the 6 patients who developed Trousseau’s syndrome, 4 patients had it beforeor during initial treatment, and 2 during recurrent/relapsed disease treatment. The 4 patientswho developed the syndrome before or during initial treatment had advanced disease: 1 instage IIIC and 3 in stage IVB. In all cases, the disease was associated with progressive distantmetastasis. The median sur vival time from the onset of Trousseau syndrome was 1 month(range: 0–6 months). Conclusion: Cer vical cancer causes Trousseau syndrome in cases of advanced disease with ashort time between the onset of the syndrome and mortality.

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