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자료유형
학술저널
저자정보
Hirokuni Takano (The Jikei University Kashiwa Hospital Kashiwa Japan) Keiko Nakajima (The Jikei University School of Medicine Tokyo Japan.) Yoko Nagayoshi (The Jikei University School of Medicine) Hiromi Komazaki (The Jikei University School of Medicine Tokyo Japan.) Jiro Suzuki (The Jikei University School of Medicine Tokyo Japan.) Hiroshi Tanabe (The Jikei University Kashiwa Hospital Kashiwa Japan) Shigeki Niimi (The Jikei University School of Medicine Tokyo Japan.) Seiji Isonishi (Jikei Daisan Hospital) Aikou Okamoto (The Jikei University School of Medicine)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.29 No.5
발행연도
2018.1
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1 - 8 (8page)

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Objective: Since there have been few large series studies to date, we investigated the relationship between Trousseau's syndrome associated with cerebral infarction and its clinical associations with ovarian cancer. Methods: In this study, we investigated the association between cerebral infarction onset and ovarian cancer. Eight-hundred twenty-seven consecutive ovarian cancer patients from 4 affiliated academic institutions were included in the study over a 12 years period. All patients were histopathologically diagnosed as epithelial ovarian cancer and were analyzed retrospectively. Results: The 27 patients (3.2%) presented with cerebral infarction during the study period, 14 patients onset prior to treatment (1.7%), and 13 patients onset after start of initial treatment (1.5%). Univariate analysis and multivariate analysis was performed for onset of Trousseau's syndrome and various clinical and pathological parameters. There was no statistical significance between the occurrence of Trousseau's syndrome with age or International Federation of Gynecology and Obstetrics (FIGO) stage; however, univariate analysis and multivariate analysis demonstrated a statistically significant association between clear cell carcinoma (CCC) and non-CCC histology. Conclusion: Thus, our results demonstrate that Trousseau's syndrome with cerebral infarction occurred with greater incidence among CCC cases compared to non-CCC cases.

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