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논문 기본 정보

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학술저널
저자정보
한승철 (Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital) 원태빈 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine) 성전 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine) 조성우 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital) 김현직 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine) 김정훈 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital) 김동영 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine) 이재서 (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine)
저널정보
대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology Vol.17 No.3
발행연도
2024.8
수록면
253 - 262 (10page)
DOI
10.21053/ceo.2024.00157

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Objectives. Sinonasal squamous cell carcinoma (SqCC) often invades the orbit. The treatment approach for sinonasal can- cer that has spread to the orbit varies across medical centers and depends on the extent of the invasion. The decision to preserve the orbit in the treatment strategy is made on a case-by-case basis and results in varying outcomes. Cur- rently, a multimodal treatment regimen, which may include surgery, chemotherapy, radiotherapy (RT), or concurrent chemoradiotherapy (CCRT), is commonly adopted for managing sinonasal cancers. This study aims to assess the prog- nosis of sinonasal SqCC with orbital invasion from various perspectives. Methods. We conducted a retrospective review of patients with primary sinonasal SqCC invading the orbit who were treat- ed at Seoul National University Hospital and Seoul National University Bundang Hospital between 2009 and 2018. The extent of the tumor, orbital invasion, treatment strategies, recurrence rates, and survival rates were analyzed. Results. Overall survival and disease-free survival (DFS) rates showed no significant differences based on the grade of or- bital invasion. When tumor resection with orbit preservation was employed as the definitive treatment, DFS was sig- nificantly extended compared to cases where surgery was not the definitive treatment (RT or CCRT). Additionally, there was no significant difference in DFS between patients who underwent orbit exenteration and those who under- went tumor resection with orbit preservation as the definitive treatment. Conclusion. Tumor resection with orbit preservation as the definitive treatment appears to be the preferred approach, pro- longing DFS and increasing the likelihood of longer-term survival in cases of SqCC with orbital invasion.

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