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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.9
- 수록면
- 710 - 725 (16page)
- DOI
- https://doi.org/10.22246/jikm.2024.45.4.710
이용수
초록· 키워드
오류제보하기
Purpose: A scoping review was conducted to assess the toxicity and safety of Ganoderma lucidum.
Methods: A literature search was conducted in several medical databases (EMBASE, Scopus, PubMed, Cochrane Library, ScieneON, and RISS) to identify studies related to G. lucidum. We extracted clinical manifestations of adverse events described in the included studies and analyzed whether the incidence of each adverse event was higher in the G. lucidum group compared to the placebo group.
Results: An initial search yielded 1,409 studies, of which 31 studies met the criteria and included in the final analysis (7 randomized controlled trials, 5 nonrandomized studies, and 19 case reports). Several gastrointestinal, respiratory, neurological, and dermatological manifestations were reported as adverse events in the included literature. However, no serious adverse events with a causal relationship to G. lucidum were reported in studies other than case reports, and no statistically significant differences in the incidence of any adverse events were observed between the G. lucidum group and the placebo group (p>0.05).
Conclusion: Our findings do not seem to support the claim that G. lucidum poses a safety risk when consumed as food or as an ingredient in food. However, given the existence of some adverse events where a causal link to G. lucidum cannot be entirely ruled out, further research and ongoing monitoring are still warranted.
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