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학술저널
저자정보
Yong Sung Kim (Digestive Disease Research Institute, Wonkwang University School of Medicine, Iksan, Korea, Good Breath Clinic, Gunpo, Gyeonggi-do Korea) Ju Yup Lee (Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea) Jung-Wook Kim (Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea) Seung Joo Kang (Department of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital Gangnam Center, Seoul, Korea) Jung Ho Park (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea) Hyun Jin Kim (Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Gyeongsangnam-do, Korea) Seung-ho Jang (Department of Psychiatry, Wonkwang University School of Medicine, Iksan, Korea) Ji-Hyeon Kim (Department of Education, Hongik University, Seoul, Korea) Jung-Hwan Oh (Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.30 No.3
발행연도
2024.7
수록면
361 - 372 (12page)
DOI
10.5056/jnm23012

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Background/AimsIrritable bowel syndrome (IBS) generally shows sex differences, and psychiatric comorbidities play an important role in its pathogenesis. We aim to measure the levels of gender roles and investigate their relationship with psychiatric factors in patients with IBS versus healthy controls. MethodsPatients diagnosed with IBS by Rome III and whose colonoscopy findings were normal were enrolled at multiple sites in Korea. The participants completed the Korean Sex Role Inventory–Short Form (KSRI-SF) to assess masculinity and femininity, the stress questionnaire, the Hospital Anxiety Depression Scale (HADS), and the 36-item Short Form Health Survey questionnaire to assess the quality of life (QOL). ResultsIn total, 102 patients with IBS (male:female = 35:67; mean age 42.6 ± 16.7 years) and 55 controls (male:female = 20:35; mean age 42.4 ± 11.1 years) were recruited. IBS patients had higher stress (9.69 ± 8.23 vs 4.56 ± 8.31, P < 0.001) and HADS scores (16.12 ± 7.17 vs 10.22 ± 5.74, P < 0.001) than the control group, but showed no significant difference in KSRI-SF scores. No significant differences in HADS and KSRI-SF scores were found between males and females. However, IBS patients whose symptoms worsened due to stress and patients with anxiety or depression had significantly lower masculinity. QOL was poorer in IBS patients than in controls. In stepwise multivariate analyses, the anxiety score, depression score, and the degree of daily life disturbance, not masculinity, were associated with the QOL of IBS patients. ConclusionsIBS patients had higher stress, more psychiatric comorbidities, and lower QOL than controls. Low masculinity, rather than sex, was associated with stress and psychological comorbidities, which deteriorated the QOL in IBS patients.

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