지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.1
- 수록면
- 1 - 19 (19page)
- DOI
- 10.1016/j.mocell.2024.100137
이용수
초록· 키워드
오류제보하기
All the information essential for life is encoded within our genome and epigenome, which orchestrates diverse cellular states spatially and temporally. In particular, the epigenome interacts with internal and external stimuli, encoding and preserving cellular experiences, and it serves as the regulatory base of the transcriptome across diverse cell types. The emergence of single-cell transcriptomic and epigenomic data collection has revealed unique omics signatures in diverse tissues, highlighting cellular heterogeneity. Recent research has documented age-related epigenetic changes at the single-cell level, alongside the validation of cellular rejuvenation through partial reprogramming, which involves simultaneous epigenetic modifications. These dynamic shifts, primarily fueled by stem cell plasticity, have catalyzed significant interest and cross-disciplinary research endeavors. This review explores the genomic and epigenomic alterations with aging, elucidating their reciprocal interactions. Additionally, it seeks to discuss the evolving landscape of rejuvenation research, with a particular emphasis on dissecting stem cell behavior through the lens of single-cell analysis. Moreover, it proposes potential research methodologies for future studies.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Epigenetic Regulations in Mammalian Cells: Roles and Profiling Techniques
Molecules and Cells
2023 .02
-
Epigenomic and transcriptomic analysis of Chronic Inflammatory Diseases
Genes & Genomics
2021 .01
-
Epigenome editing: targeted manipulation of epigenetic modifications in plants
Genes & Genomics
2022 .03
-
Cooperative Instruction of Signaling and Metabolic Pathways on the Epigenetic Landscape
Molecules and Cells
2018 .03
-
Single-Cell Toolkits Opening a New Era for Cell Engineering
Molecules and Cells
2021 .01
-
Dissecting Cellular Heterogeneity Using Single-Cell RNA Sequencing
Molecules and Cells
2019 .01
-
Prospects and challenges of epigenomics in crop improvement
Genes & Genomics
2022 .03
-
Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools
Genomics & informatics
2018 .01
-
Single-Cell Genomics for Investigating Pathogenesis of Inflammatory Diseases
Molecules and Cells
2023 .02
-
Single-Cell Molecular Barcoding to Decode Multimodal Information Defining Cell States
Molecules and Cells
2023 .02
-
The emerging role of gut hormones
Molecules and Cells
2024 .01
-
Ageing and Rejuvenation Models Reveal Changes in Key Microbial Communities Associated with Healthy Ageing
한국미생물학회 학술대회논문집
2021 .08
-
How Do Bacteria Maximize Their Cellular Assets?
한국미생물·생명공학회지
2021 .12
-
Harnessing epigenetic variability for crop improvement: current status and future prospects
Genes & Genomics
2022 .03
-
Epigenetic Changes in Fungal-bacterial Interaction Conditions and Cell Cycle Processes
한국미생물학회 학술대회논문집
2020 .10
-
Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology
Molecules and Cells
2020 .01
-
Identification of the Relationship between Cellular Traction Force and the Curvature of the Cell Edge
한국진공학회 학술발표회초록집
2020 .08
-
The Expanding World of SUMO: from Epigenetics to Adaptive Mechanisms and Cellular Aging
한국미생물학회 학술대회논문집
2020 .10
-
Gut Microbiome, a Potent Modulator of Epigenetics in Human Diseases
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2017 .06
-
The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells
Molecules and Cells
2020 .01
최근 본 자료
댓글(0)
0