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논문 기본 정보

자료유형
학술저널
저자정보
송권화 (고려대학교) Junho Park (Korea University) Hojun Lee (Korea University) Junhun Kweon (Korea University) Sunwoo Park (Gyeongsang National University) Jiyeon Ham (Chungnam National University) Fuller W. Bazer (Texas A)
저널정보
한국분자세포생물학회 Molecules and Cells Molecules and Cells Vol.47 No.1
발행연도
2024.1
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1 - 9 (9page)

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Environmental pollutants, including endocrine disruptors, heavy metals, nanomaterials, and pesticides, have been detected in various ecosystems and are of growing global concern. The potential for toxicity to non-target organisms has consistently been raised and is being studied using various animal models. In this review, we focus on pesticides frequently detected in the environment and investigate their potential exposure to livestock. Owing to the reproductive similarities between humans and pigs, various in vitro porcine models, such as porcine oocytes, trophectoderm cells, and luminal epithelial cells, are used to verify reproductive toxicity. These cell lines are being used to study the toxic mechanisms induced by various environmental toxicants, including organophosphate insecticides, pyrethroid insecticides, dinitroaniline herbicides, and diphenyl ether herbicides, which persist in the environment and threaten livestock health. Collectively, these results indicate that these pesticides can induce female reproductive toxicity in pigs and suggest the possibility of adverse effects on other livestock species. These results also indicate possible reproductive toxicity in humans, which requires further investigation.

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