지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.8
- 수록면
- 101 - 106 (6page)
- DOI
- 10.15188/kjopp.2024.08.38.4.101
이용수
초록· 키워드
오류제보하기
Natural Korean medicine has already been a great success, being used to treat various types of othopedic diseases, especially fracture and osteoporosis. In this study, we find a new mixture of herbal medicine (JGT 2.0) of five well-known Korean herbal medicine for bone healing, including Angelica gigas, Dendrobium moniliforme, Dipsaci Radix, Antler, Astragalus membranaceus, Conidium officinale, Achyranthes japonica, Messa medicate fermentata on bone fracture healing. To evaluate the efficacy of JGT 2.0, the ulna of Sprague-Dawley rats was intentionally fractured and administered JGT 2.0, followed by radiographic imaging and histological examination using H&E staining to confirm the progress of recovery over time at the fracture site. X-ray imaging showed no significant difference between groups up to 1 week after JGT 2.0 administration. However, after 4 weeks of JGT 2.0 administration, bone regeneration decreased by -15% in the control group, but increased by 23.6% in the JGT 2.0 group. In addition, the length of calluses increased by 252% in the JGT 2.0 group compared to the control group. Taken together, the results suggest that JGT may offer a novel therapeutic approach to accelerate the growth of bone calluses and promote healing of bone fractures.
목차
Introduction
Materials and Methods
Results
Discussion
References
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