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논문 기본 정보

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학술저널
저자정보
Rahul Madhukar Kashyap (Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, India) Pradeep Bhatia (Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, India) Tanvi M. Meshram (Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, India) Swati Chhabra (Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, India) Rakesh Kumar (Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, India)
저널정보
대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.28 No.2
발행연도
2024.6
수록면
201 - 208 (8page)
DOI
10.4235/agmr.23.0180

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Background: Older patients are particularly vulnerable to age-related respiratory changes. This prospective randomized controlled trial studied the effects of high and low fractions of inspired oxygen (FiO2 ) with the recruitment maneuver (RM) during extubation on lung atelectasis postoperatively in older patients undergoing major abdominal surgery. Methods: We randomized a total of 126 patients aged >60 years who underwent both elective and emergency major abdominal surgeries and met the inclusion criteria into three groups (H, HR, and LR) using computer-generated block randomization. Group H received high FiO2 (1), Group HR received high FiO2 (1) with RM followed by a positive end-expiratory pressure of 5 cm H2 O, and Group LR received low FiO2 (0.4) with RM followed by a positive end-expiratory pressure of 5 cm H2 O 10 minutes before extubation. Oxygenation and atelectasis were measured using the arterial partial pressure of oxygen (PaO2 )/FiO2 ratios and lung ultrasound score. Postoperative pulmonary complications were recorded up to 24 hours postoperatively. Results: The mean PaO2 /FiO2 at 30 minutes post-extubation was significantly higher in Groups LR and HR compared to that in Group H (390.71±29.55, 381.97±24.97, and 355.37±31.70; p<0.001). In the immediate postoperative period, the median lung ultrasound score was higher in Group H than that in Groups LR and HR (6 [5–7], 3 [3–5], and 3.5 [2.25–4.75]; p<0.001). The incidence of oxygen desaturation and oxygen requirements was higher in Group H during the postoperative period. Conclusion: The RM before extubation is beneficial in reducing atelectasis and postoperative pulmonary complications, irrespective of the FiO2 concentration used in older adults undergoing major abdominal surgeries. (Trail registration number: Reference No. CTRI/2022/04/042115; date of CTRI registration 25/02/2022; and date of enrolment of the first research participant 05/05/2022)

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