지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 81 - 91 (11page)
- DOI
- 10.5145/ACM.2024.27.2.5
이용수
초록· 키워드
오류제보하기
Although intestinal parasites are no longer considered a significant public health concernin Korea, tissue-invading parasites continue to pose clinical challenges. The diagnosisof tissue helminthiasis by recovering worms or larvae from tissues is invasive; therefore,serodiagnosis is widely used to diagnose infections caused by tissue-invading parasites.
Among the serological tests, the enzyme-linked immunosorbent assay (ELISA) is the mostcommonly used, and various antigens, including crude antigens, excretory-secretoryantigens of helminths, and cystic fluid of larval tapeworms, are used to detect specific IgGsagainst parasite antigens in the sera or cerebrospinal fluid of patients. A multi-antigen ELISAwas used to diagnose four major tissue parasitic infections: clonorchiasis, paragonimiasis,cysticercosis, and sparganosis. In addition to these four parasitic infections, ELISA remainsa valuable diagnostic method for toxocariasis, trichinellosis, fascioliasis, echinococcosis,and other diseases. A comprehensive history of the mode of transmission of the suspectedparasites and the patient’s residence in or travel to an endemic area may help in making adefinitive diagnosis. For the management of patients with eosinophilia in Korea, it is essentialto perform ELISA for the differential diagnosis of toxocariasis. Serological tests have thedisadvantage of being unable to differentiate between past and current infections, and thepossibility of cross-reactivity requires careful interpretation. It is important to note that theresults of serological tests are not necessarily conclusive and should be interpreted in thecontext of other symptoms, as well as clinical and imaging findings.
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