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논문 기본 정보

자료유형
학술저널
저자정보
Jo Ju Young (Department of Dermatology, Korea University Ansan Hospital, Ansan, Korea.) Chae Su Ji (Department of Dermatology, Korea University Ansan Hospital, Ansan, Korea.) Ryu Hwa Jung (Department of Dermatology, Korea University Ansan Hospital, Ansan, Korea.)
저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology Vol.36 No.3
발행연도
2024.6
수록면
125 - 134 (10page)
DOI
10.5021/ad.23.133

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Melasma is a prevalent hyperpigmentation condition known for its challenging treatment due to its resemblance to photoaged skin disorders. Numerous studies have shed light on the intri- cate nature of melasma, which often bears similarity to photoaging disorders. Various thera- peutic approaches, encompassing topical and systemic treatments, chemical peeling, and laser therapy, have exhibited efficacy in managing melasma in previous research. However, melasma often reoccurs despite successful treatment, primarily due to its inherent photoaged properties. Given that melasma shares features with photoaging disorders, including disruptions in the basement membrane, solar elastosis, angiogenesis, and mast cell infiltration in the dermal layer, a comprehensive treatment strategy is imperative. Such an approach might involve addressing epidermal hyperpigmentation while concurrently restoring dermal components. In this article, we provide a comprehensive review of conventional treatment methods frequently employed in clinical practice, as well as innovative treatments currently under development for melasma management. Additionally, we offer an extensive over view of the pathogenesis of melasma.

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