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논문 기본 정보

자료유형
학술저널
저자정보
김형도 (국립부곡병원) 김양태 (계명대학교) 서상수 (국립부곡병원)
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제30권 제3호(통권 제71호)
발행연도
2024.10
수록면
76 - 85 (10page)

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초록· 키워드

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Objectives: The aim of this study was to investigate how impaired decision-making, hypersensitivity to reward, and executive dysfunction in individuals with methamphetamine use disorder affect their ability to make decisions under uncertain conditions.
Methods: We conducted a study with 33 patients diagnosed with methamphetamine use disorder and 33 healthy individuals. Three tasks were administered: the Iowa Gambling Task (IGT), Game of Dice Task (GDT), and Wisconsin Card Sorting Test (WCST). We then analyzed the participants’ performance on these tasks and calculated the correlations be- tween them.
Results: Patients with methamphetamine use disorder performed poorly on all three tasks compared to the healthy individuals. Furthermore, the correlations between performances on the GDT and the later trials of the IGT were delayed in the methamphetamine use disorder group compared to the healthy group. A strong correlations were also observed between performances on the earlier trials of the IGT and the WCST in the patient group.
Conclusions: These findings suggest that executive dysfunction in individuals with methamphetamine use disorder impairs their ability to accurately estimate the probabilities of different choices. Consequently, this impairment leads to a delayed transition from uncertain to risky decisions in the IGT. The study sheds light on the neuropsychological factors that contribute to impaired decision-making under uncertainty in individuals with methamphetamine use disorder.

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