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논문 기본 정보

자료유형
학술저널
저자정보
Kazuya Kariyama (Department of Gastroenterology, Okayama City Hospital, Okayama, Japan) Kazuhiro Nouso (Department of Gastroenterology, Okayama City Hospital, Okayama, Japan) Atsushi Hiraoka (Gastroenterology Center, Ehime Prefectural Central Hospital, Matsuyama) Hidenori Toyoda (Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki) Toshifumi Tada (Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital, Himeji) Kunihiko Tsuji (Center of Gastroenterology, Teine Keijinkai Hospital, Sapporo) Toru Ishikawa (Department of Gastroenterology, Saiseikai Niigata Hospital, Niigata) Takeshi Hatanaka (Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi) Ei Itobayashi (Department of Gastroenterology, Asahi General Hospital, Asahi) Koichi Takaguchi (Department of Hepatology, Kagawa Prefectural Central Hospital, Takamatsu) Akemi Tsutsui (Department of Hepatology, Kagawa Prefectural Central Hospital, Takamatsu) Atsushi Naganuma (Departments of Gastroenterology,National Hospital Organization Takasaki General Medical Center, Takasaki) Satoshi Yasuda (Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan) Satoru Kakizaki (Clinical Research, National Hospital Organization Takasaki General Medical Center, Takasaki) Akiko Wakuta (Department of Gastroenterology, Okayama City Civic Hospital, Okayama) Shohei Shiota (Department of Gastroenterology, Okayama City Civic Hospital, Okayama) Masatoshi Kudo (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan) Takashi Kumada (Department of Nursing, Faculty of Nursing, Gifu Kyoritsu University)
저널정보
대한간암학회 Journal of Liver Cancer Journal of Liver Cancer 제24권 제1호
발행연도
2024.3
수록면
71 - 80 (10page)
DOI
10.17998/jlc.2023.09.11

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초록· 키워드

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Background/Aim: The aim of this study was to compare the therapeutic efficacy of ablation and surgery in solitary hepatocellular carcinoma (HCC) measuring ≤5 cm with a large HCC cohort database. Methods: The study included consecutive 2,067 patients with solitary HCC who were treated with either ablation (n=1,248) or surgery (n=819). Th e patients were divided into three groups based on the tumor size and compared the outcomes of the two therapies using propensity score matching. Results: No significant difference in recurrence-free survival (RFS) or overall survival (OS) was found between surgery and ablation groups for tumors measuring ≤2 cm or >2 cm but ≤3 cm. For tumors measuring >3 cm but ≤5 cm, RFS was significantly better with surgery than with ablation (3.6 and 2.0 years, respectively, P=0.0297). However, no significant difference in OS was found between surgery and ablation in this group (6.7 and 6.0 years, respectively, P=0.668). Conclusion: The study suggests that surgery and ablation can be equally used as a treatment for solitary HCC no more than 3 cm in diameter. For HCCs measuring 3-5 cm, the OS was not different between therapies; thus, ablation and less invasive therapy can be considered a treatment option; however, special caution should be taken to prevent recurrence.

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