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논문 기본 정보

자료유형
학술저널
저자정보
Nicola Carla (Graduate Health Sciences Program, Universidade de Caxias do Sul, Caxias do Sul, Brazil) Souza Vandréa de (Graduate Health Sciences Program, Universidade de Caxias do Sul, Caxias do Sul, Brazil)
저널정보
대한소아신장학회 Childhood Kidney Diseases Childhood Kidney diseases Vol.28 No.1
발행연도
2024.2
수록면
16 - 26 (11page)
DOI
10.3339/ckd.23.023

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Patients with kidney disease require frequent blood tests to monitor their kidney function, which is particularly difficult for young children and the elderly. For these people, the standard method is to evaluate serum creatinine or cystatin C or drug levels through venous sampling, but more recently, evaluation using dried blood spots has been used. This narrative review reports information from the literature on the use of dried blood spots to quantify the main markers used to detect kidney diseases. The ScienceDirect and PubMed databases were searched using the keywords: “dried blood on filter paper,” “markers of renal function,” “renal function,” “creatinine,” “cystatin C,” “urea,” “iohexol,” and “iotalamate.” Studies using animal samples were excluded, and only relevant articles in English or Spanish were considered. Creatinine was the most assessed biomarker in studies using dried blood spots to monitor kidney function, showing good performance in samples whose hematocrit levels were within normal reference values. According to the included studies, dried blood spots are a practical monitoring alternative for kidney disease. Validation parameters, such as sample and card type, volume, storage, internal patterns, and the effects of hematocrit are crucial to improving the reliability of these results.

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