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논문 기본 정보

자료유형
학술저널
저자정보
Kim Tae Hun (Division of Pulmonology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.) Song Myung Jin (Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.) 임성윤 (분당서울대학교병원) 이연주 (서울대학교) 조영재 (분당서울대학교병원)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care Vol.39 No.1
발행연도
2024.2
수록면
100 - 107 (8page)
DOI
10.4266/acc.2023.00668

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Background: New variants of the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic continue to emerge. However, little is known about the effect of these variants on clinical outcomes. This study evaluated the risk factors for poor pulmonary lung function tests (PFTs).Methods: The study retrospectively analyzed 87 patients in a single hospital and followed up by performing PFTs at an outpatient clinic from January 2020 to December 2021. COVID-19 variants were categorized as either a non-delta variant (November 13, 2020–July 6, 2021) or the delta variant (July 7, 2021–January 29, 2022).Results: The median age of the patients was 62 years, and 56 patients (64.4%) were male. Mechanical ventilation (MV) was provided for 52 patients, and 36 (41.4%) had restrictive lung defects. Forced vital capacity (FVC) and diffusion capacity of the lung for carbon monoxide (DLCO) were lower in patients on MV. Male sex (odds ratio [OR], 0.228) and MV (OR, 4.663) were significant factors for decreased DLCO. The duration of MV was associated with decreased FVC and DLCO. However, the type of variant did not affect the decrease in FVC (P=0.750) and DLCO (P=0.639).Conclusions: Among critically ill COVID-19 patients, 40% had restrictive patterns with decreased DLCO. The reduction of PFT was associated with MV, type of variants.

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