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논문 기본 정보

자료유형
학술저널
저자정보
정윤경 (경희대학교 대학원 한방소아과) 최서연 (강동경희대학교병원 한방소아과) 방미란 (강동경희대학교병원 한방소아과) 장규태 (강동경희대학교병원 한방소아과) 이보람 (한국한의학연구원 한의과학연구부)
저널정보
대한한방소아과학회 대한한방소아과학회지 대한한방소아과학회지 제38권 제1호
발행연도
2024.2
수록면
55 - 77 (23page)

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Objectives This study aimed to analyze the registration status and characteristics of clinical trials on herbal medicine (HM) and medication interventions for simple obesity in children and adolescents. Methods All interventional clinical trials registered in the International Clinical Trials Registry Platform of the World Health Organization until December 12, 2024, were collected. The study design, interventions, inclusion and exclusion criteria, and outcome measures were extracted. Results A total of 24 clinical trials (23 medications and 1 HM) were analyzed. The most common study designs were single-center, randomized controlled, parallel, and phase 2. Placebo controls were used in 87.5% of the studies, blinding was used in 79.1%, and quadruple blinding was the most common. Informed consent was obtained from 70.8% of the participants. Among the oral medications (66.6%), metformin was the most common (25%). Among the non-oral medications (29.1%), exenatide (Bydureon) was the most common intervention (42.8%). Body mass index was the most commonly reported primary outcome measure (79.1%), with most assessments performed at 6 months. Conclusions Based on the characteristics of the medication interventional clinical trial design analyzed in this study, additional high-quality multicenter traditional Korean medicine trials need to be designed in the future.

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