This study was conducted to determinean optimal soaking solution for inhibiting the texture softening of shrimp Litopenaeus vannamei pressured at high temperature (S-P/HT) in a retort, and also to optimize concentrations of 0.5% calcium chloride (CC) and 5.0% potato starch (PS) for preparation of a mixed solution (MS) and soaking time (ST) in the MS. On the basis of the results of expressible drip (4.6%), water holding capacity (95.1%), hardness (18.4 N/cm2) and sensory texture (7.2 score), the MS was found to be the optimal soaking solution for inhibition of texture softening under S-P/HT conditions, The concentrations of CC (X₁, %), PS (X₂, %), and ST (X₃, min) were selected as independent variables, and hardness (Y₁), springiness (Y₂) and sensory texture (Y₃) were selected as dependent variables. The optimal conditions of X₁, X₂, and X₃ were 0.51%, 6.34%, and 364 min, respectively. Under the optimal conditions, the experimental values of Y₁, Y₂ and Y₃ were 18.3±0.8 N/cm², 4.4±0.3 mm and 7.7±0.2, respectively, which did not diffr significantly from the predicted values (P>0.05). In conclusion, the optimized models of X₁, X₂, and X₃ for the preparation of S-P/HT using CC-PS were suitably fitted.