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자료유형
학술저널
저자정보
장동현 (Department of Public Healthcare Service Seoul National University Bundang Hospital Seongnam Korea) Park Seung Min (Department of Emergency Medicine Seoul National University Bundang Hospital Seoul National University College of Medicine Seoul Korea.) 이동건 (분당서울대학교병원) 김동원 (한림대학교부속춘천성심병원) 임창우 (Department of Emergency Medicine Seoul National University Bundang Hospital Seongnam Korea) Jo You Hwan (Department of Emergency Medicine Seoul National University Bundang Hospital Seongnam Korea.) 이귀자 (경동대학교 응급구조학과)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care 제38권 제1호
발행연도
2023.2
수록면
104 - 112 (9page)
DOI
10.4266/acc.2022.01389

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Background There are conflicting results regarding the association between body mass index and the prognosis of cardiac arrest patients. We investigated the association of the composition and distribution of muscle and fat with neurologic outcomes at hospital discharge in successfully resuscitated out-of-hospital cardiac arrest (OHCA) patients. Methods This prospective, single-centre, observational study involved adult OHCA patients, conducted between April 2019 and June 2021. The ratio of total skeletal muscle, upper limb muscle, lower limb muscle, and total fat to body weight was measured using InBody S10, a bioimpedance analyser, after achieving the return of spontaneous circulation. Restricted cubic spline curves with four knots were used to examine the relationship between total skeletal muscle, upper limb muscle, and lower limb muscle relative to total body weight and neurologic outcome at discharge. Multivariable logistic regression analysis was performed to assess an independent association. Results A total of 66 patients were enrolled in the study. The proportion of total muscle and lower limb muscle positively correlated with the possibility of having a good neurologic outcome. The proportion of lower limb muscle showed an independent association in the multivariable analysis (adjusted odds ratio, 2.29; 95% confidence interval, 1.06–13.98), and its optimal cut-off value calculated through receiver operating characteristic curve analysis was 23.1%, which can predict a good neurological outcome. Conclusions A higher proportion of lower limb muscle to body weight was independently associated with the probability of having a good neurologic outcome in OHCA patients.

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