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자료유형
학술저널
저자정보
Hiroto Kageyama (Department of Neurosurgery Hyogo Medical University) Kotaro Tatebayashi (Department of Neurosurgery Hyogo Medical University) Shinichi Yoshimura (Department of Neurosurgery Hyogo Medical University) Toshiki Endo (Division of Neurosurgery Tohoku Medical and Pharmaceutical University) Kazutoshi Hida (Department of Neurosurgery Sapporo Azabu Neurosurgical Hospital) Masaki Mizuno (Department of Minimum-Invasive Neurospinal Surgery Mie University)
저널정보
대한척추신경외과학회 Neurospine Neurospine 제20권 제2호
발행연도
2023.6
수록면
678 - 691 (14page)
DOI
10.14245/ns.2346390.195

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Objective: Intramedullary spinal cord tumors (IMSCTs) are uncommon and difficult to treat. Studies examining the efficacy of rare IMSCT surgery in the elderly are limited. We conducted a subanalysis using multicenter retrospective-historical data provided by the Ja pan Neurospinal Society to compare surgical outcomes between older and younger adults with IMSCTs. Methods: We classified patients with IMSCTs into younger (aged 18–64 years) or older ( ≥ 65 years) groups. The primary outcomes of “improved” or “worsened” from the preop erative period to 6 months after surgery were evaluated using the modified McCormick scale (mMCs). A favorable outcome was defined as an mMCs grade of I/II at 6 months. Results: Among 841 patients registered, there were 658 younger (78.2%) and 183 older pa tients (21.8%) evaluated using mMCs at 6 months. Median preoperative mMCs grades were significantly worse in older patients than in younger patients. Neither the “improved” nor “worsened” rate differed significantly between the groups (28.1% vs. 25.1%; crude odds ra tio [cOR], 0.86; 95% confidence interval [CI], 0.59–1.25; adjusted OR [aOR], 0.84; 95% CI, 0.55–1.28; 16.9% vs. 23.0%; cOR, 1.47; 95% CI, 0.98–2.20; aOR, 1.28; 95% CI, 0.83–1.97). Favorable outcomes were significantly less common among older adults in the univariate analysis but were not significant in the multivariate analysis (66.4% vs. 53.0%; cOR, 0.57; 95% CI, 0.41–0.80; aOR, 0.77; 95% CI, 0.50–1.19). In both younger and older patients, preoperative mMCs accurately predicted favorable outcomes. Conclusion: Age alone is not a sufficient reason to prohibit surgery for IMSCTs.

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