지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background : Anticholinergic drugs (ACDs) are used for treating various clinical conditions of the elderly. However, caution is needed due to their several central and peripheral adverse effects including urinary retention (UR). UR can extend hospitalization period and increase the burden of polypharmacy due to ureter catheter insertion or additional drug therapy. The aim of this study was to analyze current status of ACD-induced UR and risk factors in older patients.
Methods : The study retrospectively reviewed patients aged 65 years and older who were first prescribed oral ACDs from July to September 2020. We measured anticholinergic burden using Korean Anticholinergic Burden Scale (KABS) and total number of ACDs. We also analyzed risk factors associated with UR.
Results : Of a total of 1,883 patients, 115 (6.1%) patients developed UR. In the UR group, the KABS and total number of ACDs were significantly increased from the time of first administration to the time of UR (p < 0.001). They were not significantly different between UR and non-UR groups at the time of first administration. However, at the time of UR (last administration in the non-UR group), both were higher in the UR group (p < 0.001). Multivariate logistic regression analysis showed that age 85 years and older, male, Charlson Comorbidity Index of 3 and more, comorbidity related to UR, history of surgery, and the total number of ACDs were significant risk factors for UR. The odds ratio of UR was 4.84 in patients with two ACDs (95% CI: 2.57-9.09, p < 0.001) and 10.60 in those with three or more ACDs (95% CI: 4.27-26.30, p < 0.001) compared to patients with one ACD.
Conclusion : High anticholinergic burden was associated with a higher incidence of UR.
Therefore, pharmacist intervention is necessary to prevent UR adverse effects in the elderly who are taking multiple ACDs or in a high-risk group.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Introduction to Umbrella Reviews as a Useful Evidence-Based Practice
지질·동맥경화학회지
2023 .01
-
Predictive factors for flexible ureterorenoscopy requirement after rigid ureterorenoscopy in cases with renal pelvic stones sized 1 to 2 cm
Investigative and Clinical Urology
2015 .01
-
Secondary surgery for vesicoureteral reflux after failed endoscopic injection: Comparison to primary surgery
Investigative and Clinical Urology
2016 .01
-
Characteristics of urinary retention in female inpatients managed with medical treatments
Investigative and Clinical Urology
2015 .01
-
Relation of Urinary Retention and Functional Recovery in Stroke Patients During Rehabilitation Program
Annals of Rehabilitation Medicine
2017 .01
-
Hepatoprotective Effect of Uncaria rhynchophylla on Thioacetamide-Induced Liver Fibrosis Model
대한의생명과학회지
2021 .09
-
노인에서 항콜린성 약물의 사용
노인정신의학
2020 .01
-
The Impact of Undernutrition Risk on Rehabilitation Outcomes in Ischemic Stroke Survivors: A Hospital-Based Study
뇌신경재활
2024 .04
-
National Practice Pattern and Time Trends in Treatment of Upper Urinary Tract Calculi in Korea: a Nationwide Population-Based Study
Journal of Korean Medical Science
2016 .01
-
Hepcidin and iron parameters in children with anemia of chronic disease and iron deficiency anemia
Blood Research
2017 .01
-
Rapidly quantitative detection of Nosema ceranae in honeybees using ultra-rapid real-time quantitative PCR
Journal of Veterinary Science
2021 .05
-
Adventitial Cystic Disease of the Iliac Artery with a Connection to the Hip Joint
Vascular Specialist International
2018 .01
-
Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis
Allergy, Asthma & Immunology Research
2019 .01
-
Effect of urinary retention on the surgical outcome of holmium laser enucleation of the benign prostatic hyperplasia
Investigative and Clinical Urology
2023 .01
-
Circulating Low Absolute CD4+ T Cell Counts May Predict Poor Prognosis in Extranodal NK/T-Cell Lymphoma Patients Treating with Pegaspargase-Based Chemotherapy
Cancer Research and Treatment
2019 .01
-
어지럼증, 식욕부진, 전신권태감 등을 동반한 만성 질환에 의한 빈혈 환자의 한방치료 1례
대한한방내과학회지
2021 .10
-
Inadvertent Stenting and Percutaneous Aspiration for Treatment of Adventitial Cystic Disease in the Popliteal Artery: A Case Report
Vascular Specialist International
2022 .06
-
부자추출물의 골격근 세포에서의 에너지 조절 작용
한방비만학회지
2016 .01
-
Long-term Outcomes of Sacral Nerve Stimulation in Pelvic Floor Dysfunctions
International Neurourology Journal
2021 .12
-
Significance of albumin to globulin ratio as a predictor of febrile urinary tract infection after ureteroscopic lithotripsy
Journal of Yeungnam Medical Science
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0