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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.6
- 수록면
- 321 - 325 (5page)
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초록· 키워드
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RNAs are pivotal molecules acting as messengers of genetic informationand regulatory molecules for cellular developmentand survival. From birth to death, RNAs face constant cellulardecision for the precise control of cellular function and activity.
Most eukaryotic cells employ conserved machineries forRNA decay including RNA silencing and RNA quality control(RQC). In plants, RQC monitors endogenous RNAs and degradesaberrant and dysfunctional species, whereas RNA silencingpromotes RNA degradation to repress the expression ofselected endogenous RNAs or exogenous RNA derived fromtransgenes and virus. Interestingly, emerging evidences haveindicated that RQC and RNA silencing interact with each bysharing target RNAs and regulatory components. Such interactionshould be tightly organized for proper cellular survival.
However, it is still elusive that how each machinery specificallyrecognizes target RNAs. In this review, we summarize recentadvances on RNA silencing and RQC pathway and discusspotential mechanisms underlying the interaction betweenthe two machineries.
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