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논문 기본 정보

자료유형
학술저널
저자정보
Kim Minjeong (Department of Psychiatry Sungkyunkwan University College of Medicine Samsung Medical Center Seoul Republic of Korea) Lee Jiye (Department of Psychiatry Sungkyunkwan University College of Medicine Samsung Medical Center Seoul Republic of Korea) Kim Nambeom (Department of Biomedical Engineering Research Center Gachon University Incheon Republic of Korea) Hwang Yunjee (Department of Brain and Cognitive Engineering Korea University Seoul Republic of Korea) Lee Kyung Hwa (Department of Psychiatry and Center for Sleep and Chronobiology Seoul National University College of Medicine and Hospital Seoul Republic of Korea) Lee Jooyoung (Department of Psychiatry Sungkyunkwan University College of Medicine Samsung Medical Center Seoul Republic of Korea) Lee Yu Jin (Department of Psychiatry and Center for Sleep and Chronobiology Seoul National University College of Medicine and Hospital Seoul Republic of Korea) Kim Seog Ju (Department of Psychiatry Sungkyunkwan University College of Medicine Samsung Medical Center Seoul Republic of Korea)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제20권 제5호
발행연도
2023.5
수록면
439 - 444 (6page)
DOI
10.30773/pi.2022.0285

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Objective This study investigated whether sleep and stress mutually interact to induce changes in white matter integrity.Methods Diffusion tensor imaging (DTI) was conducted on 36 participants (male=22, female=14; mean age=38.33±12.78 years). Participants were divided into three groups depending on their sleep quality and stress levels: poor sleepers with stress, poor sleepers without stress, and good sleepers. Sleep quality and stress level were evaluated using the Pittsburgh Sleep Quality Index and the Life Experiences Survey, respectively. Fractional anisotropy (FA) values were calculated employing DTI tractography.Results After controlling for age and sex, poor sleepers with stress exhibited a lower FA of the left inferior cerebellar peduncle (ICP) than did poor sleepers without stress (t=2.81, p=0.02). Poor sleepers without stress showed a higher FA of the right middle longitudinal fasciculus (MdLF) than did good sleepers (t=3.35, p=0.006).Conclusion The current study reports the effects of sleep, stress, and their interaction on the white matter integrities of the ICP and MdLF. ICP change seems to be associated with sleep disturbances related to stress, while MdLF change would be associated with sleep disturbances unrelated to stress.

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