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논문 기본 정보

자료유형
학술저널
저자정보
Choi Youngha (Severance Children's Hospital Endocrine Research Institute Yonsei University College of Medicine Seoul Korea) Jung Se Yong (Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Korea) Park Jung Min (Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Korea) Suh Junghwan (Severance Children's Hospital Endocrine Research Institute Yonsei University College of Medicine Seoul Korea) Shin Eun Jung (Inha University Hospital Incheon Korea) Chae Hyun Wook (Gangnam Severance Hospital Yonsei University College of Medicine Seoul Korea) Kim Ho-Seong (Severance Children's Hospital Endocrine Research Institute Yonsei University College of Medicine Seoul Korea) Kwon Ahreum (Severance Children's Hospital Endocrine Research Institute Yonsei University College of Medicine Seoul Korea)
저널정보
대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatric Endocrinology & Metabolism 제28권 제2호
발행연도
2023.6
수록면
144 - 148 (5page)
DOI
10.6065/apem.2142218.109

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Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function. In this report, we describe a case of a teenage boy who developed dilated cardiomyopathy due to hypothyroidism and was considered to undergo heart transplantation. Levothyroxine monotherapy was initiated but produced no improvement. Thereafter, a combination therapy of liothyronine and levothyroxine was administered, and heart function was gradually restored; he recovered completely after 6 months. Cardiac myocytes respond more specifically to liothyronine than to levothyroxine. Therefore, we suggest that liothyronine and levothyroxine combination therapy should be considered rather than levothyroxine monotherapy for hypothyroidism accompanied by heart disease.

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