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논문 기본 정보

자료유형
학술저널
저자정보
Cong Liang (Nanfang Hospital Southern Medical University Guangzhou China) Ping Liu (Nanfang Hospital) Shan Kang (The Fourth Hospital of Hebei Medical University Shijiazhuang China) Weili Li (Nanfang Hospital Southern Medical University Guangzhou China) BiLiang Chen (Fourth Military Medical University) Mei Ji (the First Affiliated Hospital of Zhengzhou University Zhengzhou China) Chunlin Chen (Nanfang Hospital)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.34 No.2
발행연도
2023.3
수록면
1 - 18 (18page)
DOI
https://doi.org/10.3802/jgo.2023.34.e20

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Objective: This study aimed to identif y the risk factors for genitourinar y fistulas and delayedfistula recognition after radical hysterectomy for cer vical cancer. Methods: This study was a retrospective analysis of data collected in the Major Surgicalcomplications of Cer vical Cancer in China (MSCCCC) database from 2004–2016. Data onsociodemographic characteristics, clinical characteristics, and hospital characteristics wereextracted. Differences in the odds of genitourinar y fistula development were investigatedwith multivariate logistic regression analyses, and differences in the time to recognition ofgenitourinar y fistula were assessed by Kruskal–Wallis test. Results: In this study, 23,404 patients met the inclusion criteria. Surger y in a cancer center,a women’s and children’s hospital, a facility in a first-tier city, or southwest region, stage IIA,type C1 hysterectomy, laparoscopic surger y and ureteral injur y were associated with a higherrisk of ureterovaginal fistula (UVF) (p<0.050). Surger y in southwest region, bladder injur y andlaparoscopic surger y were associated with greater odds of vesicovaginal fistula (VVF) (p<0.050). Surger y at cancer centers and high-volume hospitals was associated with an increase in themedian time to UVF recognition (p=0.016; p=0.005). International Federation of Gynecologyand Obstetrics (FIGO) stage IIA1-IIB was associated with delayed recognition of VVF (p=0.040). Conclusion: Intraoperative urinar y tract injur y and surgical approach were associated withdifferences in the development of UVFs and VVFs. Patients who under went surger y in cancercenters and high-volume hospitals were more likely to experience delayed recognitionof UVF. Patients with FIGO stage IIA1-IIB disease were more likely to experience delayedrecognition of VVF.

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