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논문 기본 정보

자료유형
학술저널
저자정보
Seo Hyobin (Department of Radiology Human Medical Imaging and Intervention Center Seoul Korea.) Jin Kwang Nam (Department of Radiology SMG-SNU Boramae Medical Center Seoul Korea.) Ji Sang Park (Department of Radiology Konkuk University Chungju Hospital) Kang Koung Mi (Department of Radiology Seoul National University College of Medicine Seoul National University Hospital Seoul Korea.) Eun Kyung Lee (Department of Radiology Gangnam Center Seoul National University Hospital Healthcare System) 이지예 (서울대학교병원 영상의학과) Yoo Roh-Eul (Department of Radiology Seoul National University College of Medicine Seoul National University Hospital Seoul Korea.) 박영주 (Department of Internal Medicine Seoul National University College of Medicine Seoul Korea) 김지훈 (서울대학교병원)
저널정보
대한초음파의학회 ULTRASONOGRAPHY ULTRASONOGRAPHY Vol.42 No.2
발행연도
2023.4
수록면
275 - 285 (11page)
DOI
10.14366/usg.22111

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Purpose: This study evaluated thyroid cancer risk in a lung cancer screening population according to the presence of an incidental thyroid nodule (ITN) detected on low-dose chest computed tomography (LDCT).Methods: Of 47,837 subjects who underwent LDCT, a lung cancer screening population according to the National Lung Screening Trial results was retrospectively enrolled. The prevalence of ITN on LDCT was calculated, and the ultrasonography (US)/fine-needle aspiration (FNA)–based risk of thyroid cancer according to the presence of ITN on LDCT was compared using the Fisher exact or Student t-test as appropriate.Results: Of the 2,329 subjects (female:male=44:2,285; mean age, 60.9±4.9 years), the prevalence of ITN on LDCT was 4.8% (111/2,329). The incidence of thyroid cancer was 0.8% (18/2,329, papillary thyroid microcarcinomas [PTMCs]) and was higher in the ITN-positive group than in the ITN-negative group (3.6% [4/111] vs. 0.6% [14/2,218], P=0.009). Among the 2,011 subjects who underwent both LDCT and thyroid US, all risks were higher (P<0.001) in the ITNpositive group than in the ITN-negative group: presence of thyroid nodule on US, 94.1% (95/101) vs. 48.6% (928/1,910); recommendation of FNA according to the American Thyroid Association guideline and Korean Thyroid Imaging Reporting and Data System guideline, 41.2% (42/101) vs. 2.4% (46/1,910) and 39.6% (40/101) vs. 1.9% (37/1,910), respectively.Conclusion: Despite a higher risk of thyroid cancer in the LDCT ITN-positive group than in the ITN-negative group in a lung cancer screening population, all cancers were PTMCs. A heavy smoking history may not necessitate thorough screening US for thyroid incidentalomas.

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