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논문 기본 정보

자료유형
학술저널
저자정보
Jung Young Hee (Department of Neurology Myongji Hospital Hanyang University College of Medicine Goyang Korea.) Ha Eun-Hye (Department of Pulmonary and Critical Care Medicine Myongji Hospital Hanyang University College of Medicine Goyang Korea.) Park Junli (Department of Family Medicine Myongji Hospital Hanyang University College of Medicine Goyang Korea.) Choe Kang Won (Department of Infectious Disease Myongji Hospital Hanyang University College of Medicine Goyang Korea.) Lee Wang Jun (The Office of Chief Executive Officer and Chairman Department of General Surgery Myongji Hospital Hanyang University College of Medicine Goyang Korea.) Jo Dong Ho (Department of Infectious Disease Myongji Hospital Hanyang University College of Medicine Goyang Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.38 No.11
발행연도
2023.3
수록면
1 - 11 (11page)
DOI
10.3346/jkms.2023.38.e83

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초록· 키워드

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Background: We aimed to investigate the factors associated with neurological manifestations of post-coronavirus disease 2019 (COVID-19) conditions. Methods: We retrospectively collected data from 440 patients who visited our post-COVID-19 clinic more than 4 weeks after severe acute respiratory syndrome coronavirus 2 infection. We analyzed the prevalence of different neurological symptoms (brain fog, memory impairment, headache, and dizziness) and assessed the associated factors. Results: Brain fog was the most common symptom, observed in 170 patients (38.6%), followed by headaches (n = 137, 31.1%), dizziness (n = 128, 29%), and memory impairment (n = 104, 23.6%). Brain fog was associated with hyposmia or hypogeusia (odds ratio [OR], 2.54; P < 0.001), Fatigue Severity Scale (FSS) (OR, 1.06; P < 0.001), and Hospital Anxiety and Depression Scale-Anxiety (OR, 1.09; P = 0.037). Memory impairment was associated with sleep problems (OR, 2.83; P < 0.001), FSS (OR, 1.05; P < 0.001), and age (OR, 1.02; P = 0.015). Headache was associated with sleep problems (OR, 2.28; P = 0.001), sex (OR, 1.68; P = 0.042), and FSS (OR, 1.04; P < 0.001). Dizziness was associated with sleep problems (OR, 2.88; P < 0.001), and FSS (OR, 1.04; P < 0.001). The incidence of brain fog (P < 0.001), memory impairment (P < 0.001), dizziness (P = 0.007), and headache (P = 0.045) accompanied by hyposmia and hypogeusia was higher in patients with the aforementioned symptoms than in those without. Conclusion: This study suggests that there is a relationship between neurological symptoms and other clinical factors, such as fatigue, depression, anxiety, hyposmia, and hypogeusia.

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