지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.4
- 수록면
- 1 - 11 (11page)
- DOI
- 10.1038/s12276-023-00960-y
이용수
초록· 키워드
오류제보하기
Damage to the colon mucus barrier, the first line of defense against microorganisms, is an important determinant of intestinal diseases such as inflammatory bowel disease and colorectal cancer, and disorder in extraintestinal organs. The mucus layer has attracted the attention of the scientific community in recent years, and with the discovery of new mucosal components, it has become increasingly clear that the mucosal barrier is a complex system composed of many components. Moreover, certain components are jointly involved in regulating the structure and function of the mucus barrier. Therefore, a comprehensive and systematic understanding of the functional components of the mucus layer is clearly warranted. In this review, we summarize the various functional components of the mucus layer identified thus far and describe their unique roles in shaping mucosal structure and function. Furthermore, we detail the mechanisms underlying mucus secretion, including baseline and stimulated secretion. In our opinion, baseline secretion can be categorized into spontaneous Ca2+ oscillation-mediated slow and continuous secretion and stimulated secretion, which is mediated by massive Ca2+ influx induced by exogenous stimuli. This review extends the current understanding of the intestinal mucus barrier, with an emphasis on host defense strategies based on fortification of the mucus layer.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Development of Gut-Mucus Chip for Intestinal Absorption Study
BioChip Journal
2023 .06
-
Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis
Experimental and Molecular Medicine
2021 .05
-
Development of Gut-mucus Chip for Intestinal Absorption Study
한국생물공학회 학술대회
2021 .04
-
Development of Gut-mucus Chip Mimicking Intestinal Mucosa for Intestinal Absorption Study
한국생물공학회 학술대회
2021 .10
-
지속 가능한 항력 저감을 위한 생체모방형 mucus-infused surface 개발
한국가시화정보학회 학술발표대회 논문집
2019 .06
-
Nitric Oxide-mediated Mucus-walking Zwitterionic Polymer Nanocomplex for Relief of Acute Respiratory Distress Syndrome
한국고분자학회 학술대회 연구논문 초록집
2023 .04
-
미꾸라지 피부에서 영감을 받아 제작된 다기능성 점액질 코팅 표면
대한기계학회 춘추학술대회
2020 .12
-
한우 암소 발정유기 시 점액누출에 따른 인공수정 후 임신율과 배사멸 효과
한국산학기술학회 논문지
2023 .11
-
미꾸라지 피부의 삼차원 가시화
한국가시화정보학회 학술발표대회 논문집
2019 .12
-
Contributions of the microbiome to intestinal inflammation in a gut-on-a-chip
Nano Convergence
2022 .02
-
Anoctamin 1/TMEM16A controls intestinal Cl− secretion induced by carbachol and cholera toxin
Experimental and Molecular Medicine
2019 .01
-
Roles of intestinal epithelial cells in the maintenance of gut homeostasis
Experimental and Molecular Medicine
2017 .01
-
Bacterial secretion system as a controllable drug-delivery platform
한국생물공학회 학술대회
2019 .04
-
Optimization of Secretion of Recombinant Proteins in Bacillus subtilis
한국생물공학회 학술대회
2015 .10
-
VR 시뮬레이터 개발을 위한 컴포넌트 프레임워크
한국CDE학회 학술발표회 논문집
2016 .01
-
Engineering of Pseudomonas putida for heterologous protein secretion
한국생물공학회 학술대회
2018 .04
-
Evaluation of Intestinal Epithelial Barrier Function in Inflammatory Bowel Diseases Using Murine Intestinal Organoids
조직공학과 재생의학
2020 .01
-
Development of Secretion System for the Enhanced Production of Recombinant Proteins in Corynebacterium glutamicum
한국생물공학회 학술대회
2015 .10
-
Optimum growth condition and electrical properties of CuGa0.5In0.5Se₂:Co(0.5 wt %) single crystal thin film for solar cell using hot wall epitaxy method
한국태양에너지학회 학술대회논문집
2017 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0