Adverse Events Following Immunizations in Infants Under 1 Year of Age in Lorestan Province, Western Iran

khatereh Anbari; Koruosh Ghanadi; Alireza Toulabipour; Daryuosh Jamebozuorghi; Parastoo Baharvand

doi:10.3961/jpmph.22.540

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자료유형: 학술저널

저자정보: khatereh Anbari (Community Medicine Department School of Medicine Social Determinant of Health Research Center Lores) Koruosh Ghanadi (Internal Medicine Department School of Medicine Lorestan University of Medical Science Khorramabad) Alireza Toulabipour (Lorestan University of Medical Science Khorramabad Iran) Daryuosh Jamebozuorghi (Lorestan University of Medical Science Khorramabad Iran) Parastoo Baharvand (Community Medicine Department School of Medicine Social Determinant of Health Research Center Lores)

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제56권 제2호

발행연도: 2023.3

수록면: 172 - 179 (8page)

DOI: 10.3961/jpmph.22.540

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Objectives: Vaccination is an important intervention for preventing disease and reducing disease severity. Universal vaccination programs have significantly reduced the incidence of many dangerous diseases among children worldwide. This study investigated the side effects after immunization in infants under 1 year of age in Lorestan Province, western Iran.Methods: This descriptive analytical study included data from all children <1 year old in Lorestan Province, Iran who were vaccinated according to the national schedule in 2020 and had an adverse event following immunization (AEFI). Data were extracted from 1084 forms on age, sex, birth weight, type of birth, AEFI type, vaccine type, and time of vaccination. Descriptive statistics (frequency, percentage) were calculated, and the chi-square test and Fisher exact test were used to assess differences in AEFIs according to the abovelisted variables.Results: The most frequent AEFIs were high fever (n=386, 35.6%), mild local reaction (n=341, 31.5%), and swelling and pain (n=121, 11.2%). The least common AEFIs were encephalitis (n=1, 0.1%), convulsion (n=2, 0.2%), and nodules (n=3, 0.3%). Girls and boys only showed significant differences in mild local reactions (p=0.044) and skin allergies (p=0.002). The incidence of lymphadenitis (p<0.001), severe local reaction (p<0.001), mild local reaction (p=0.007), fainting (p=0.032), swelling and pain (p=0.006), high fever (p=0.005), and nodules (p<0.001) showed significant differences based on age at vaccination.Conclusions: Immunization is a fundamental public health policy for controlling vaccine-preventable infectious diseases. Although vaccines such as the Bacillus Calmette-Guérin vaccine, oral poliovirus vaccine, and pentavalent vaccine are well-researched and reliable, AEFIs are inevitable.

#Vaccination #Adverse events #Infants #Incidence #Iran

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khatereh Anbari

소속기관 Community Medicine Department School of Medicine Social Determinant of Health Research Center Lores