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논문 기본 정보

자료유형
학술저널
저자정보
Nham Eliel (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Yoon Jin Gu (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Choi Min Joo (Department of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.) Seo Yu Bin (Division of Infectious Diseases, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.) Lee Jacob (Division of Infectious Diseases, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.) Choi Won Suk (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Hyun Hakjun (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Seong Hye (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Noh Ji Yun (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Song Joon Young (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Kim Woo Joo (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.) Cheong Hee Jin (Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.Vaccine Innovation Center-KU Medicine (VIC-K), Seoul, Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.39 No.5
발행연도
2024.2
수록면
1 - 7 (7page)
DOI
10.3346/jkms.2024.39.e45

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초록· 키워드

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Background: In Korea, there are no surveillance programs for vaccines that are not included in the national immunization program (NIP), and vaccine safety monitoring in the adult population is inadequate. This study aimed to establish a safety monitoring system for nonNIP vaccines in adults. Methods: Frequently administered non-NIP vaccines were selected. Individuals were included if they received at least one of the selected vaccines at a participating institution and provided informed consent. Solicited and unsolicited adverse events were monitored using questionnaires sent through text messages on days 1, 3, 7, 28, and 90 post-vaccination. Selected adverse events of special interest (AESIs) were monitored monthly by retrospective review of electronic medical records. Causality was assessed according to the Korea Disease Control and Prevention Agency guidelines. Results: Four vaccines (tetanus-diphtheria-pertussis [Tdap], pneumococcal conjugate 13-valent [PCV13], live zoster vaccine [ZVL], and recombinant zoster vaccine [RZV]) were selected, and their safety profiles were monitored at four tertiary hospitals and 10 primary care clinics. The response rates of the questionnaires on post-vaccination days 1, 7, 28, and 90 were 99.2%, 93.6%, 81.0%, and 48.7%, respectively. Of 555 AESI identified over 10 months, 10 cases received one of the selected non-NIP vaccines within 90 days of the event. Conclusion: We are establishing the first safety monitoring system for selected non-NIP vaccines in Korea since September 2022 and report its progress as of July 2023. However, continuous government support is essential for its maintenance and improvement.
#Vaccines #Safety #Monitoring #Surveillance #Non-NIP

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