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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 187 - 193 (7page)
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Primary signet ring neuroendocrine tumors of the liver are extremely rare tumors. Morphologically, they mimic signet ring cell adenocarcinomas; however, the absence of mucin by special stains and the expression of neuroendocrine markers help to diagnose these tumors. We herein report a case of a 47-year-old female who presented with multiple solid and cystic lesions in both liver lobes, which were initially suggested to be biliary cystadenocarcinoma on imaging. Liver biopsy of the lesion revealed the presence of a signet ring neoplasm with diffuse expression of synaptophysin and pan-cytokeratin. The case was subsequently diagnosed as a primary hepatic signet ring neuroendocrine tumor. The patient was offered 3 cycles of chemotherapy and is well preserved after 14 months of diagnosis. Although this is an extremely rare entity, its possibility should be considered in the differential diagnosis of neoplasms characterized by signet ring cell morphology.
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참고문헌 (17)
참고문헌 신청
Klimstra DS / 2019 / Digestive system tumours, WHO classification of tumours series / International Agency for Research on Cancer :263~264
Edmondson HA / 1958 / Atlas of tumor pathology / Armed Forces Institute of Pathology :105~109
Dala R / 2006 / Primary hepatic neuroendocrine carcinoma : an underdiagnosed entity / Ann Diagn Pathol 10:28~31
Xue Y / 2020 / Morphologic variants of pancreatic neuroendocrine tumors : clinicopathologic analysis and prognostic stratification / Endocr Pathol 31:239~253
Xu C / 2020 / Gastric signet ring cell neuroendocrine tumor : report of a case / Zhonghua Bing Li Xue Za Zhi 49:941~943
Edmondson HA / 1958 / Atlas of tumor pathology / Armed Forces Institute of Pathology :105~109
Dala R / 2006 / Primary hepatic neuroendocrine carcinoma : an underdiagnosed entity / Ann Diagn Pathol 10:28~31
Xue Y / 2020 / Morphologic variants of pancreatic neuroendocrine tumors : clinicopathologic analysis and prognostic stratification / Endocr Pathol 31:239~253
Xu C / 2020 / Gastric signet ring cell neuroendocrine tumor : report of a case / Zhonghua Bing Li Xue Za Zhi 49:941~943
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