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논문 기본 정보

자료유형
학술저널
저자정보
Soyoung Park (Chungbuk National University) Hakhyun Kim (Chungbuk National University) Ji-Houn Kang (Chungbuk National University) Byeong-Teck Kang (Chungbuk National University) Mhan-Pyo Yang (Chungbuk National University)
저널정보
대한수의학회 Korean Journal of Veterinary Research(대한수의학회지) Korean Journal of Veterinary Research(구 대한수의학회지) 제59권 제1호
발행연도
2019.5
수록면
9 - 15 (7page)

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초록· 키워드

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In canine acute pancreatitis (AP), inappropriate release and activation of zymogen proteases within the pancreas results in the consumption of serum antiproteases. The aim of this study was to examine whether the serum concentrations of α₂-macroglobulin (A2MG), α1-antitrypsin (A1AT), and C-reactive protein (CRP) differ between dogs with AP and healthy dogs. Twenty healthy dogs and 20 dogs with AP were included in this study. Concentrations of A2MG, A1AT, and CRP were measured in the sera of healthy dogs and dogs diagnosed with AP. Serum A2MG and A1AT concentrations were significantly lower in dogs with AP than in healthy dogs, whereas the serum CRP concentration was significantly higher. In addition, the concentrations of A2MG and A1AT were significantly higher in AP survivors than in AP non-survivors, while the CRP concentration was significantly lower. However, in both AP survivors and non-survivors, the CRP concentrations showed a negative correlation with A2MG concentrations but not with A1AT. These findings indicate that serum antiproteases and CRP concentrations might be associated with the mortality rate of AP in dogs.

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Abstract
Introduction
Materials and Methods
Results
Discussion
References

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