지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Scrub typhus caused byOrientia tsutsugamushi manifests as fever, headache, myalgia and sometimes central nervous system dysfunction after mite bite. Eschar is an important diagnostic factor for scrub typhus but can be absent in about 30% of cases. We report a 6yearold boy with scrub typhus meningoencephalitis, in whom diagnosis was late due to absence of eschar and direct exposure history. He was transferred to our hospital due to altered mental status and seizures following sustained fever. Previously, he had been diagnosed with aseptic meningitis as cerebrospinal fluid examination showed pleocytosis with normal range of glucose and protein. No pathogen had been proven and no abnormalities had been found in brain magnetic resonance imaging. On admission to our hospital, electroencephalography showed diffuse delta slowing with bilateral frontal sharps and scrub typhus antibody was positive, although the patient had no eschar. Family historytaking revealed his grandmother had been recently treated for scrub typhus and his father helping her farm and often cared for the patient wearing his working pants, as a possible vehicle of infection. Recovery was gradually upon treatment with clarithromycin, intravenous methylprednisolone and immunoglobulin. As scrub typhus can be present without eschar and can be transmitted through contaminated clothes, it needs to be considered for patients presenting with meningoencephalitis in a vulnerable season.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Yum KS / 2011 / Scrub typhus meningo-encephalitis with focal neurologic signs and associated brain MRI abnormal findings: literature review / Clin Neurol Neurosurg 113:250~253
Pai H / 1997 / Central nervous system involvement in patients with scrub typhus / Clin Infect Dis 24:436~440
Boorugu H / 2014 / Central nervous system involvement in scrub typhus / Trop Doct 44:36~37
Misra UK / 2015 / Neurological manifestations of scrub typhus / J Neurol Neurosurg Psychiatry 86:761~766
Koh GC / 2010 / Diagnosis of Scrub Typhus / Am J Trop Med Hyg 82:368~370
Pai H / 1997 / Central nervous system involvement in patients with scrub typhus / Clin Infect Dis 24:436~440
Boorugu H / 2014 / Central nervous system involvement in scrub typhus / Trop Doct 44:36~37
Misra UK / 2015 / Neurological manifestations of scrub typhus / J Neurol Neurosurg Psychiatry 86:761~766
Koh GC / 2010 / Diagnosis of Scrub Typhus / Am J Trop Med Hyg 82:368~370
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