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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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This study analyzed characteristics of Moutan Cortex Radicis extract as a raw material for cosmetics and evaluated antioxidant activity,anti-inflammatory effect, anti-bacterial effect, and cytotoxicity of active components of Moutan Cortex Radicis extract. As a result, in DPPH radical elimination ability, concentration of 1000 ?g/ml showed most similar result as the positive comparison group Vit.C of 84.7% of radical elimination ability, and ABTS radical elimination ability showed slightly lower value compare to the positive comparison group, however, it was identified that the elimination ability increased as the concentration level increased as it showed 66.1% of radical elimination ability in 1000 ?g/ml of Moutan Cortex Radicis concentration. Polyphenol and flavonoid contents each showed 106.4?0.003 mg/g and 112.9?0.004 content, and when NO formation inhibition of Raw 264.7 cell induced by LPS was researched, generation amount of NO decreased as the concentration of Moutan Cortex Radicis extract increased. Also,propionibacterium acnes high antibacterial activity was observed in 100 mg/ml concentration level for acne germs, and high antibacterial activity was observed from 10 mg/ml for staphylococcus aureus. Lastly, Moutan Cortex Radicis extract did not have cytotoxicity when the concentration level was low. Based on above results, this study suggests that active component of Moutan Cortex Radicis extract has possibilities of application as a raw material of natural cosmetic product that has antioxidant effect as well as anti-inflammatory, antibacterial,and non-toxic effects.
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참고문헌 (41)
참고문헌 신청
고경숙 / 2013 / 황금추출물의 항산화활성및세포독성연구 / 한국미용예술학회지 14(2):233~243
고경숙 / 2012 / 자화지정 메탄올추출물의 항산화효능에 관한연구 / 한국미용학회지 18(5):1082~1086
강경아 / 2005 / 산화적 스트레스에 대한 생약 추출물의 항 산화활성 검색 / 생약학회지 36(3):159~163
김연숙 / 2011 / 왕쥐똥나무잎 추출물의 항산화 활성 / 한국식품영양과학회지 40(12):1642~1647
김영언 / 2009 / 송이(Tricholoma matsutake Sing.)의 ABTS Radical 소거능과 암세포 생장 억제효능의 검색 / 한국식품영양과학회지 38(5):555~560
고경숙 / 2012 / 자화지정 메탄올추출물의 항산화효능에 관한연구 / 한국미용학회지 18(5):1082~1086
강경아 / 2005 / 산화적 스트레스에 대한 생약 추출물의 항 산화활성 검색 / 생약학회지 36(3):159~163
김연숙 / 2011 / 왕쥐똥나무잎 추출물의 항산화 활성 / 한국식품영양과학회지 40(12):1642~1647
김영언 / 2009 / 송이(Tricholoma matsutake Sing.)의 ABTS Radical 소거능과 암세포 생장 억제효능의 검색 / 한국식품영양과학회지 38(5):555~560
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