Apatite-forming ability and antibacterial property of Ag-CaO-SiO2/polyetherether ketone composites

J. C. Lee; S. H. Rhee; J. Y. Choi; I. Noh; C. Ohtsuki; I. Y. Kim

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자료유형: 학술저널

저자정보: J. C. Lee (서울대학교) S. H. Rhee (서울대학교) J. Y. Choi (서울대학교) I. Noh (서울대학교) C. Ohtsuki (Nagoya University) I. Y. Kim (Nagoya University)

저널정보: 한양대학교 세라믹공정연구센터 Journal of Ceramic Processing Research Journal of Ceramic Processing Research 제17권 제7호

발행연도: 2016.7

수록면: 732 - 737 (6page)

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Ceramic biomaterials have been used to recover the lost functions of the damaged bones by direct fusion with the bones. CaOSiO2systemhas been known as a bioactive material that has an ability to form apatite on the surface of the bones inside thebody fluid. Applications of biomaterials could require the use of excess amount of antibiotics during transplantation to preventany infections or microbism. Ag ion has been known for its unique biological properties of antibiosis. We already reported thatCaO-SiO2gels prepared by a sol-gel method can be used as inorganic fillers for osteoconductive composites because theyshowed apatite-forming ability in a simulated body fluid. In this study, we synthesized 30CaO70SiO2(CS) gel powders modifiedwith Ag ions ranging from 0 to 100 ppm to provide antibacterial property. Using the Ag-modified CS powders, compositeswere prepared by combining with polyetheretherketone (PEEK), which was used as a polymer matrix. Apatite formation ina simulated body fluid was observed on all the composites regardless of Ag contents. The composites consisting of CS modifiedwith Ag ions suppressed multiplication of E.coli. Consequently, CS/PEEK modified with Ag ions not only retained its abilityof forming HAp but also gained an antibacterial property.

#Sol-Gel #Ag-30CaO ? 70SiO2 gels #Composite #Polyetheretherketone #Antibacterial property

참고문헌 (19)

참고문헌 신청

L. L. Hench / 1971 / J. Biomed. Mater. Res. Symp 2:117~141

L.L. Hench / 1993 / An Introduction to Bioceramics / World Scientific :41~62

T. Yamamuro / 1990 / Handbook of bioactive ceramics Vol. 1 / CRC Press Inc :343~351

C. Ohtsuki / 1993 / J. Ceram. Soc. Japan 99:1~6

C. Ohtsuki / 1992 / J. Non-Cryst. Solids 143:84~92

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