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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
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- 대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제38권 제8호
- 발행연도
- 2016.8
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- 1 - 9 (9page)
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Background: The objective of this study was to evaluate xenograft degradation velocity when treated with 4-hexylresorcinol (4HR).
Methods: The scapula of a cow was purchased from a local grocery, and discs (diameter 8 mm, thickness 1 mm) were prepared by trephine bur. Discs treated with 4HR were used as the experimental group. Untreated discs were used as the control. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), antibacterial test, endotoxin test, and scanning electron microscopy (SEM) were performed on the discs. In vivo degradation was evaluated by the rat calvarial defect model.
Results: The XRD and FT-IR results demonstrated successful incorporation of 4HR into the bovine bone.
The experimental disc showed antibacterial properties. The endotoxin test yielded results below the level of endotoxin contamination. In the SEM exam, the surface of the experimental group showed needle-shaped crystal and spreading of RAW264.7 cells. In the animal experiments, the amount of residual graft was significantly smaller in the experimental group compared to the control group (P = 0.003).
Conclusions: In this study, 4HR was successfully incorporated into bovine bone, and 4HR-incorporated bovine bone had antibacterial properties. In vivo experiments demonstrated that 4HR-incorporated bovine bone showed more rapid degradation than untreated bovine bone.
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참고문헌 (26)
참고문헌 신청
Hyun-Suk Cha / 2016 / Frequency of bone graft in implant surgery / Maxillofacial Plastic Reconstructive Surgery 38(03):1~4
김은석 / 2015 / Various autogenous fresh demineralized tooth forms for alveolar socket preservation in anterior tooth extraction sites: a series of 4 cases / Maxillofacial Plastic Reconstructive Surgery 37(8):1~7
Kassim B / 2014 / Current perspectives on the role of ridge (socket) preservation procedures in dental implant treatment in the aesthetic zone / Aust Dent J 59(1):48~56
Sariibrahimoglu K / 2014 / Tuning the degradation rate of calcium phosphate cements by incorporating mixtures of polylactic-co-glycolic acid microspheres and glucono-deltalactone microparticles / Tissue Eng Part A 20(21-22):2870~2882
Ding X / 2011 / Improved bioabsorbability of synthetic hydroxyapatite through partial dissolution-precipitation of its surface / J Mater Sci Mater Med 22(5):1247~1255
김은석 / 2015 / Various autogenous fresh demineralized tooth forms for alveolar socket preservation in anterior tooth extraction sites: a series of 4 cases / Maxillofacial Plastic Reconstructive Surgery 37(8):1~7
Kassim B / 2014 / Current perspectives on the role of ridge (socket) preservation procedures in dental implant treatment in the aesthetic zone / Aust Dent J 59(1):48~56
Sariibrahimoglu K / 2014 / Tuning the degradation rate of calcium phosphate cements by incorporating mixtures of polylactic-co-glycolic acid microspheres and glucono-deltalactone microparticles / Tissue Eng Part A 20(21-22):2870~2882
Ding X / 2011 / Improved bioabsorbability of synthetic hydroxyapatite through partial dissolution-precipitation of its surface / J Mater Sci Mater Med 22(5):1247~1255
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