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Comparative study of new bone formation capability of zirconia bone graft material in rabbit calvarial
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논문 기본 정보

Type
Academic journal
Author
Journal
The Korean Academy Of Prosthodontics The Journal of Advanced of Prosthodontics The Journal of Advanced of Prosthodontics 제10권 제3호 KCI Accredited Journals
Published
2018.1
Pages
167 - 176 (10page)

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Comparative study of new bone formation capability of zirconia bone graft material in rabbit calvarial
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Research history (2)

2018

Comparative study of new bone formation capability of zirconia bone graft material in rabbit calvarial
Ik-Jung Kim ,  Sooyeon Shin The Journal of Advanced of Prosthodontics 2018.01 Academic journal

2015

토끼의 두개골 결손부에서 지르코니아 골이식재의 신생골 형성에 대한 비교 연구
김익중 치의학과 보철학 전공 2015.01 Thesis
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Abstract· Keywords

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PURPOSE. The purpose of this study was to compare the new bone formation capability of zirconia with those of other synthetic bone grafts. MATERIALS AND METHODS. Twelve rabbits were used and four 6-mm diameter transcortical defects were formed on each calvaria. Each defect was filled with Osteon II (Os), Tigran PTG (Ti), and zirconia (Zi) bone grafts. For the control group, the defects were left unfilled. The rabbits were sacrificed at 2, 4, and 8 weeks. Specimens were analyzed through micro computed tomography (CT) and histomorphometric analysis. RESULTS. The Ti and Zi groups showed significant differences in the amount of newly formed bone between 2 and 4 weeks and between 2 and 8 weeks (P<.05). The measurements of total bone using micro CT showed significant differences between the Os and Ti groups and between the Os and Zi groups at 2 and 8 weeks (P<.05). Comparing by week in each group, the Ti group showed a significant difference between 4 and 8 weeks. Histomorphometric analysis also showed significant differences in new bone formation between the control group and the experimental groups at 2, 4, and 8 weeks (P<.05). In the comparison of newly formed bone, significant differences were observed between 2 and 4 weeks and between 2 and 8 weeks (P<.05) in all groups. CONCLUSION. Zirconia bone graft material showed satisfactory results in new bone formation and zirconia could be used as a new synthetic bone graft material.

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References (50)

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Marx RE / 1994 / Clinical application of bone biology to mandibular and maxillary reconstruction / Clin Plast Surg 21:377~392 google schola Hoexter DL / 2002 / Bone regeneration graft materials / J Oral Implantol 28:290~294 Crossref Quattlebaum JB / 1988 / Antigenicity of freeze-dried cortical bone allograft in human periodontal osseous defects / J Periodontol 59:394~397 Crossref Sogal A / 1999 / Risk assessment of bovine spongiform encephalopathy transmission through bone graft material derived from bovine bone used for dental applications / J Periodontol 70:1053~1063 Crossref Vaccaro AR / 2002 / The role of the osteoconductive scaffold in synthetic bone graft / Orthopedics 25:s571~s578 google schola

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