지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 539 - 544 (6page)
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초록· 키워드
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Human endogenous retroviruses (HERVs) mediate struc-tural variation and genomic instability based on their multiple copy number, inherent ability to mobilize via reverse transcriptase, and high sequence similarity. More-over, they undergo multiple amplification and retrotransposition events, resulting in the widespread distribution of complete or partial retroviral sequences throughout the primate genome. As such, HERV elements have played important biological roles in ge-nome evolution, and their long terminal repeat (LTR) elements contain numerous regulatory sequences, including effective promoters, enhancers, polyadenylation signals, and transcription factor-binding sites. Lastly, HERV elements are capable of influencing the expression of neighboring genes, a process that also contributed to primate evolution.
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참고문헌 (5)
참고문헌 신청
Hong-Seok Ha / 2011 / Development of GEBRET: a web-based analysis tool for retroelements in primate genomes / Genes & Genomics 33(6):679~684
Jae-Won Huh / 2009 / Gain of New Exons and Promoters by Lineage-Specific Transposable Elements-Integration and Conservation Event on CHRM3 Gene / Molecules and Cells 28(2):111~117
Sang-Je Park / 2010 / Analysis of the Molecular and Regulatory Properties of Active Porcine Endogenous Retrovirus Gamma-1 Long Terminal Repeats in Kidney Tissues of the NIH-Miniature Pig / Molecules and Cells 30(4):319~325
Sin, H. S. / 2006 / Transcriptional control of the HERV-H LTR element of the GSDML gene in human tissues and cancer cells / Archives of Virology 151(10):1985~1994
신호수 / 2007 / Long Terminal Repeats of Human Endogenous Retrovirus H Family Provide Alternative Polyadenylation Signals to NADSYN1 Gene / Genes & Genomics 29(3):395~401
Jae-Won Huh / 2009 / Gain of New Exons and Promoters by Lineage-Specific Transposable Elements-Integration and Conservation Event on CHRM3 Gene / Molecules and Cells 28(2):111~117
Sang-Je Park / 2010 / Analysis of the Molecular and Regulatory Properties of Active Porcine Endogenous Retrovirus Gamma-1 Long Terminal Repeats in Kidney Tissues of the NIH-Miniature Pig / Molecules and Cells 30(4):319~325
Sin, H. S. / 2006 / Transcriptional control of the HERV-H LTR element of the GSDML gene in human tissues and cancer cells / Archives of Virology 151(10):1985~1994
신호수 / 2007 / Long Terminal Repeats of Human Endogenous Retrovirus H Family Provide Alternative Polyadenylation Signals to NADSYN1 Gene / Genes & Genomics 29(3):395~401
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