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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.4
- 수록면
- 69 - 75 (7page)
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초록· 키워드
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The secret of chemical diversity and function of specialized metabolites in medicinal plants will be unveiled by study of functional genomics at an unprecedentedly rapid rate in the coming years. This is mostly ascribed to the remarkable advancement in the high-throughput DNA sequencing together with other omics technologies such as metabolomics, in particular, due to drastic reduction in the cost of acquiring, storing and analyzing massive omics datasets. Once the genes involved in a biosynthetic pathway of specialized compounds in plants are elucidated, synthetic biology or genome editing can be applied to produce the target compounds in an engineered organism or to manipulate the pathway in planta. Coupled with these advancements in pathway elucidation approaches, modern plant biotechnology strategies are bound to significantly contribute to the sustainable development goals set by United Nations.
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참고문헌 (66)
참고문헌 신청
Afendi FM / 2012 / KNApSAcK family databases: integrated metabolite-plant species databases for multifaceted plant research / Plant Cell Physiol 53:e1
Arabidopsis Genome I / 2000 / Analysis of the genome sequence of the flowering plant Arabidopsis thaliana / Nature 408:796~815
Asada K / 2013 / A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle / Plant Cell 25:4123~4134
Bortesi L / 2015 / The CRISPR/Cas9 system for plant genome editing and beyond / Biotechnol Adv 33:41~52
Brown S / 2015 / De novo production of the plant-derived alkaloid strictosidine in yeast / Proc Natl Acad Sci 112:3205~3210
Arabidopsis Genome I / 2000 / Analysis of the genome sequence of the flowering plant Arabidopsis thaliana / Nature 408:796~815
Asada K / 2013 / A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle / Plant Cell 25:4123~4134
Bortesi L / 2015 / The CRISPR/Cas9 system for plant genome editing and beyond / Biotechnol Adv 33:41~52
Brown S / 2015 / De novo production of the plant-derived alkaloid strictosidine in yeast / Proc Natl Acad Sci 112:3205~3210
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