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논문 기본 정보

자료유형
학술저널
저자정보
채민석 (을지대학교 의과대학 을지병원 이비인후과학교실) 김지선 (을지대학교) 안영민 (을지대학교) 김호찬 (을지대학교)
저널정보
대한이비인후과학회 부산,울산,경남 지부회 임상이비인후과 임상이비인후과 제32권 제3호
발행연도
2021.12
수록면
221 - 227 (7page)
DOI
10.35420/jcohns.2021.32.3.221

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초록· 키워드

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Background and Objectives: To evaluate relationship between vitamin D and severity of obstructive sleep apnea (OSA) in Korean children. Materials and Methods: This study was conducted on children aged 5 to 17 years who had polysomnography and blood 25-hydroxyvitamin D (25(OH)D) measurements from January 2015 to July 2018 in our Medical Center. Apnea hypopnea index (AHI) 1 or higher was considered to be an OSA patient, and obesity was defined when the body mass index (BMI) was 95% or more of each age and gender. Vitamin D level was checked through 25(OH)D in blood. Results: Of the total 109 children included in the study, the mean blood concentration of 25(OH)D was 19.5±7.1 ng/mL and AHI was 5.4±15.8 /h. Sixty-five children (59.6%) were Vitamin D deficient. In bivariate correlation analysis, 25(OH)D level and BMI z-score (r=?0.24, p=0.01), AHI (r=?0.22, p=0.02) showed a statistically significant negative correlation. Forty children were obese, and the 25(OH)D in the obese group was statistically significantly lower (p=0.08). In the obese group, 25(OH)D was not statistically correlated with AHI, but obstructive portion of AHI obstructive showed a statistically negative correlation (r=?0.36 , p=0.02). Compared to the non-OSA group, the OSA group had a statistically significantly lower 25(OH)D (p=0.04). Conclusions: Vitamin D level was lower in obese children and children with OSA. There was a correlation between the severity of OSA and vitamin D deficiency.

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