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논문 기본 정보

자료유형
학술저널
저자정보
차소연 (Department of Radiology and Center for Imaging Science Samsung Medical Center Sungkyunkwan Universi) 고은영 (성균관대학교) 한부경 (Department of Radiology and Center for Imaging Science Samsung Medical Center Sungkyunkwan Universi) 고은숙 (Department of Radiology and Center for Imaging Science Samsung Medical Center Sungkyunkwan Universi) 최지수 (Department of Radiology and Center for Imaging Science Samsung Medical Center Sungkyunkwan Universi) 박고운 (성균관대학교 의과대학 삼성서울병원 영상의학과) 이정언 (삼성서울병원)
저널정보
한국유방암학회 Journal of Breast Cancer Journal of Breast Cancer Vol.24 No.4
발행연도
2021.8
수록면
377 - 388 (12page)
DOI
10.4048/jbc.2021.24.e35

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Purpose: To evaluate the accuracy of magnetic resonance imaging (MRI)-guided breast biopsy. Methods: We retrospectively reviewed the clinical data of 111 consecutive patients referred for MRI-guided breast biopsy after mammography and breast ultrasound between May 2009 and April 2019. After excluding 37 patients without follow-up images (> 2 years), 74 patients (74 lesions) were finally included. We reviewed the histologic results of MRI-guided biopsy and subsequent surgery, post-biopsy management, and breast cancer development during follow-up. We investigated the false-negative rate, ductal carcinoma in situ (DCIS) underestimation, atypical ductal hyperplasia (ADH) underestimation rate, and technical failure rate of MRI-guided biopsy. Results: Among 74 scheduled MRI-guided biopsies, six were canceled because biopsy was deemed unnecessary, while three failed due to technical difficulties (technical failure rate: 3/68, 4.4%). MRI-guided biopsy was performed in 65 patients, of which 18 patients were diagnosed with malignant lesions, 46 with benign lesions, and one with ADH bordering on DCIS. Subsequent surgery (n = 27) showed DCIS underestimation in three cases (3/7, 43%), ADH underestimation in two cases (1/2, 50%), as well as seven concordant benign and 11 concordant malignant lesions. The overall false-negative rate was 4.3% (2/46). Thirty-eight out of 48 benign lesions were followed-up (median period, 5.8 years; interquartile range, 4.1 years) without subsequent surgery. Thirty-seven concordant benign lesions were stable (n = 27) or disappeared (n = 10); however, the size of one discordant benign lesion increased on follow-up MRI and it was diagnosed as DCIS after 1 year. Conclusion: MRI-guided biopsy is an accurate method for exclusion of malignancy with a very low false-negative rate.

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