Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

Tae Chung Hyun; 이준행; 민병훈; 김경미; 이풍렬; 김재준

Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

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Type: Academic journal

Author: Tae Chung Hyun 이준행 민병훈 김경미 이풍렬 김재준

Journal: 거트앤리버 발행위원회 Gut and Liver Gut and Liver 제10권 제1호 KCI Accredited Journals SCOPUS

Published: 2016.1

Pages: 63 - 68 (6page)

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Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

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Background/Aims: Repeat endoscopy with biopsy is often performed in patients with previously diagnosed gastric cancer to determine further treatment plans. However, biopsy results may differ from the original pathologic report. We reviewed patients who had a negative biopsy after referral for gastric cancer. Methods: A total of 116 patients with negative biopsy results after referral for biopsy-proven gastric cancer were enrolled. Outside pathology slides were reviewed. Images of the first and second endoscopic examinations were reviewed. We reviewed the clinical history from referral to the final treatment. Results: Eighty-eight patients (76%) arrived with information about the lesion from the referring physician. Among 96 patients with available outside slides, the rate of interobserver variation was 24%. Endoscopy was repeated at our institution; 85 patients (73%) were found to have definite lesions, whereas 31 patients (27%) had indeterminate lesions. In the group with definite lesions, 71% of the lesions were depressed in shape. The most common cause of a negative biopsy was mistargeting. In the group with indeterminate lesions, 94% had insufficient information. All patients with adequate follow-up were successfully treated based on the findings in the follow-up endoscopy. Conclusions: A negative biopsy after referral for biopsy-proven gastric cancer is mainly caused by mistargeting and insufficient information during the referral.

#Stomach #Neoplasms #Biopsy #Gastroscopy

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Kyu-Won Jung / 2012 / Prediction of Cancer Incidence and Mortality in Korea, 2012 / Cancer Research and Treatment 44(1):15~31

Kim Y / 2011 / Overview of the National Cancer screening programme and the cancer screening status in Korea / Asian Pac J Cancer Prev 12:725~730

Hatfield AR / 1975 / Importance of the site of endoscopic gastric biopsy in ulcerating lesions of the stomach / Gut 16:884~886

Misumi A / 1978 / Evaluation of fibergastroscopic biopsy in the diagnosis of gastric cancer: a study of 339 cases / Gastroenterol Jpn 13:255~263

Faigel DO / 2003 / Tissue sampling and analysis / Gastrointest Endosc 57:811~816

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