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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.3
- 수록면
- 10 - 15 (6page)
- DOI
- https://doi.org/10.13041/jpvm.2018.42.1.10
이용수
초록· 키워드
오류제보하기
To elucidate the effect of cellular phone electromagnetic wave (EMW) exposure on the developing cerebellar cortex of neonatal Sprague-Dawley rats, animals were exposed to cellular phone electromagnetic waves for 1 hr per day for 3 weeks. At the end of the experimental period, animals were sacrificed by cardiac perfusion, after which histological samples were prepared and observed microscopically. In the EMW exposure group, external granule cells were remained partially in the external granular layer without migrating into the internal granular layer. In addition, dark stained shrunken Purkinje cells with pyknotic nuclei increased and the outline of cells became irregular and showed degenerative signs, such as mitochondrial swelling and disrupted cristae. Moreover, the cisternae of rough endoplasmic reticula and Golgi complex were severely swollen. Bergmann glial cells adjacent to the dark stained Purkinje cells were swollen and cytoplasmic organelles were scant. Dark stained shrunken granule cells were also observed and the outline of cells was irregular. The results of the present study suggest that cellular phone EMW exposure to neonatal Sprague-Dawley rats leads to a partial delay of early migration of cerebellar cortical cells and degenerative changes in Purkinje cells, Bergmann glial cells and granule cells.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Akdag MZ / 2010 / Effects of extremely low-frequency magnetic field on caspase activities and oxidative stress values in rat brain / Biol Trace Elem Res 138:238~249
Cragg B / 1985 / Natural loss of Purkinje cells durind development and increased loss with alcohol / Brain Res 325:151~160
Feychting M / 2005 / EMF and health / Ann Rev Public Health 26:165~189
Gonzalez-Burgos I / 2005 / Cerebellar granule cell and Bergmann glial cell maturation in the rat is disrupted by pre and post-natal exposure to moderate levels of ethanol / Int J Devl Neuroscience 23:383~388
Goodlett CR / 1997 / Alcohol-induced Purkinje cell loss with a single binge exposure in neonatal rats; a stereological study of temporal windows of vulnerability / Alcohol Clin Exp Res 21:738~744
Cragg B / 1985 / Natural loss of Purkinje cells durind development and increased loss with alcohol / Brain Res 325:151~160
Feychting M / 2005 / EMF and health / Ann Rev Public Health 26:165~189
Gonzalez-Burgos I / 2005 / Cerebellar granule cell and Bergmann glial cell maturation in the rat is disrupted by pre and post-natal exposure to moderate levels of ethanol / Int J Devl Neuroscience 23:383~388
Goodlett CR / 1997 / Alcohol-induced Purkinje cell loss with a single binge exposure in neonatal rats; a stereological study of temporal windows of vulnerability / Alcohol Clin Exp Res 21:738~744
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