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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 124 - 128 (5page)
- DOI
- https://doi.org/10.13041/jpvm.2017.41.3.124
이용수
초록· 키워드
오류제보하기
This study investigated the synergistic effects of a combination of cephalexin and gentamicin (CCG) against Streptococcus spp. isolated from bovine milk. Minimum inhibitory concentrations (MICs) and fractional inhibitory concentration (FIC) index were determined for 12 bacteria isolated from 12 bovine farms in Gyeongnam province. The MIC ranges of cephalexin, gentamicin and CCG were 0.25-0.5, 0.5-2.0 and 0.06-0.125 μg/mL, respectively. In addition, the FIC index range of CCG against the isolates was 0.32-0.34, showing a synergistic effect in the checkboard assay. In conclusion, CCG has a high antibacterial activity against Streptococcus isolates and may be utilized in the treatment of bovine streptococcal mastitis.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Boonyayatra S / 2016 / Antimicrobial resistance of biofilm-forming Streptococcus agalactiae isolated from bovine mastitis / J Vet Sci Technol 7:374
Bradley AJ / 2002 / Bovine mastitis: An evolving disease / Vet J 164:116~128
Buyck JM / 2015 / Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1monocytes / Antimicrob Agents Chemother 59:258~268
Clinical and Laboratory Standards Institute / 2008 / Performance standard for antimicrobial disk and dilution susceptibility tests for bacterial isolated from animals; Approved standard - Third edition. CLSI document M31-A3
Ganière JP / 2009 / Synergistic interactions between cefalexin and kanamycin in Mueller–Hinton broth medium and in milk / J Appl Microbiol 107:117~125
Bradley AJ / 2002 / Bovine mastitis: An evolving disease / Vet J 164:116~128
Buyck JM / 2015 / Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1monocytes / Antimicrob Agents Chemother 59:258~268
Clinical and Laboratory Standards Institute / 2008 / Performance standard for antimicrobial disk and dilution susceptibility tests for bacterial isolated from animals; Approved standard - Third edition. CLSI document M31-A3
Ganière JP / 2009 / Synergistic interactions between cefalexin and kanamycin in Mueller–Hinton broth medium and in milk / J Appl Microbiol 107:117~125
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