지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
The structure determination using twinned crystals is challenging although several algorithms have been developed fordetwinning the X-ray data. Our crystal of the C-terminal domain 2 and 3 of Ski7 (Ski7-D2/3), a key part of non-stop mRNAdecay has a perfect twin with the twin operator [h, -h-k, -l]. Many different efforts for phasing with multiple anomalousdispersion techniques using selenomethionine substituted wild-type and mutant proteins were not successful andthe phases were obtained through the molecular replacement method using recently reported structure of C-terminalGTPase domain of Ski7 from Saccharomyces cerevisiae. The overall structure of Ski7-D2/3 is very similar to that of thecorresponding domain of ribosome-associated GTPases including eIF5B, eEF1α, and eRF3. Domains 2 and 3 form aβ-barrel structure containing several structurally deviated long connecting loops. Although the linker between domain 2and 3 is very flexible, the relative orientation between them is virtually the same among all structures, showing that theSki7-D2/3 does not show major conformational movement upon contacting with G domain.
목차
등록된 정보가 없습니다.
참고문헌 (44)
참고문헌 신청
Adams, P. D / 2010 / PHENIX : a comprehensive Python-based system for macromolecular structure solution / Acta Crystallogr D Biol Crystallogr 66:213~221
Atkinson, G. C / 2015 / The evolutionary and functional diversity of classical and lesser-known cytoplasmic and organellar translational GTPases across the tree of life / BMC Genomics 16:78
Breyer, W. A / 1999 / On the molecular-replacement problem in the presence of merohedral twinning : structure of the N-terminal half-molecule of human lactoferrin / Acta Crystallogr D Biol Crystallogr 55:129~138
Chandra, N / 1998 / Structural evidence for the presence of a secondary calcium binding site in human alphalactalbumin / Biochemistry 37:4767~4772
Chen, L / 2010 / Structure of the Dom34-Hbs1 complex and implications for no-go decay / Nat Struct Mol Biol 17:1233~1240
Atkinson, G. C / 2015 / The evolutionary and functional diversity of classical and lesser-known cytoplasmic and organellar translational GTPases across the tree of life / BMC Genomics 16:78
Breyer, W. A / 1999 / On the molecular-replacement problem in the presence of merohedral twinning : structure of the N-terminal half-molecule of human lactoferrin / Acta Crystallogr D Biol Crystallogr 55:129~138
Chandra, N / 1998 / Structural evidence for the presence of a secondary calcium binding site in human alphalactalbumin / Biochemistry 37:4767~4772
Chen, L / 2010 / Structure of the Dom34-Hbs1 complex and implications for no-go decay / Nat Struct Mol Biol 17:1233~1240
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
기후변화가 스키 관광 수요에 미치는 영향: 기상요소의 비선형 효과를 중심으로
한국기후변화학회지
2024 .10
-
Analytical technique of electric machines for digital twins based on multi-domain model
한국자기학회 학술연구발표회 논문개요집
2024 .05
-
Application of DMSO to Improve Ski-slope effect in Direct PCR
한국분석과학회 학술대회
2020 .11
-
ON SOME UNBOUNDED DOMAINS FOR A MAXIMUM PRINCIPLE
순수 및 응용수학
2016 .01
-
현대 패션에 나타난 트위닝 경향과 내적 의미
한국생활과학회지
2017 .08
-
Characterization of αX I-Domain Binding to Receptors for Advanced Glycation End Products (RAGE)
Molecules and Cells
2017 .05
-
Crystal structure analysis using X-ray Diffraction
한국분석과학회 학술대회
2017 .05
-
KAPLANSKY-TYPE THEOREMS IN GRADED INTEGRAL DOMAINS
대한수학회보
2015 .01
-
Methods to evaluate the twin formation energy: comparative studies of the atomic simulations and in-situ TEM tensile tests
한국현미경학회지
2020 .01
-
A HALF-CENTERED STAR-OPERATION ON AN INTEGRAL DOMAIN
대한수학회지
2017 .01
-
X-ray structural analysis of electrode materials for rechargeable batteries: Practical examples
한국분석과학회 학술대회
2021 .05
-
Pullbacks of $\mathcal{C}$-hereditary domains
대한수학회보
2018 .01
-
Determination of magnetic domain-wall types via observing Dzyaloshinskii-Moriya interaction-induced domain expansion patterns
한국자기학회 학술연구발표회 논문개요집
2015 .11
-
A Novel Inhibitor of Translation Initiation Factor eIF5B in Saccharomyces cerevisiae
Journal of Microbiology and Biotechnology
2024 .06
-
A new characterization of Pr\"ufer $v$-multiplication domains
한국수학논문집
2015 .01
-
An Ensemble Approach to Domain Adaptation in Sentiment Analysis
Journal of The Korean Data Analysis Society
2019 .01
-
Trace Properties and Integral Domains, III
대한수학회보
2022 .03
-
Structure of Domain Walls in Magnetic Minerals
대한지질학회 학술대회
2017 .10
-
Some remarks on $S$-valuation domains
대한수학회논문집
2024 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0